Aricept and Shock - a phase IV clinical study of FDA data

Summary:

Shock is reported as a side effect among people who take Aricept (donepezil hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Seroquel, and have Dementia alzheimer's type.

The phase IV clinical study analyzes which people have Shock when taking Aricept. It is created by eHealthMe based on reports of 23,732 people who have side effects when taking Aricept from the FDA, and is updated regularly.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

What is Shock?

Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin) is found to be associated with 1,213 drugs and 1,755 conditions by eHealthMe. Check the latest studies of Shock.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

23,732 people reported to have side effects when taking Aricept.
Among them, 86 people (0.36%) have Shock.

Among these 86 people:

How long have people been on Aricept when they have Shock? *

What is the gender of people who have Shock when taking Aricept? *

female: 52.94 %
male: 47.06 %

What is the age of people who have Shock when taking Aricept? *

What are other drugs people take besides Aricept? *

What are other side effects people have besides Shock? *

Hypotension (abnormally low blood pressure): 18 people, 20.93%
Dehydration (dryness resulting from the removal of water): 15 people, 17.44%
Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 13 people, 15.12%
Acute Kidney Failure: 13 people, 15.12%
Bradycardia (abnormally slow heart action): 11 people, 12.79%
Depressed Level Of Consciousness: 11 people, 12.79%
Fainting (loss of consciousness and postural tone): 9 people, 10.47%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 9 people, 10.47%
Tremor (trembling or shaking movements in one or more parts of your body): 9 people, 10.47%
General Physical Health Deterioration (weak health status): 8 people, 9.30%

What are the existing conditions these people have? *

Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 31 people, 36.05%
High Blood Pressure: 13 people, 15.12%
Depression: 6 people, 6.98%
Parkinson's Disease: 5 people, 5.81%
Tardive Dyskinesia (a disorder that involves involuntary movements): 4 people, 4.65%
Polymyalgia Rheumatica (pain in many muscles): 3 people, 3.49%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 3.49%
Enlarged Prostate: 3 people, 3.49%
Psychotic Disorder: 2 people, 2.33%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Aricept and have Shock?

- Check whether Shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aricept:

Aricept (24,756 reports)

Shock treatments and more:

Shock (28,534 reports)

Browse all side effects of Aricept:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shock:

Shock (1,213 drugs)

Browse all the conditions that are associated with Shock:

Shock (1,755 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on donepezil hydrochloride (the active ingredients of Aricept) and Aricept (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.