Arixtra and Depression - a phase IV clinical study of FDA data

Summary:

Depression is reported as a side effect among people who take Arixtra (fondaparinux sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Dilaudid, and have Polycythaemia vera.

The phase IV clinical study analyzes which people have Depression when taking Arixtra. It is created by eHealthMe based on reports of 9,755 people who have side effects when taking Arixtra from the FDA, and is updated regularly.

What is Arixtra?

Arixtra has active ingredients of fondaparinux sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 9,830 Arixtra users. Check the latest studies of Arixtra.

What is Depression?

Depression is found to be associated with 3,168 drugs and 4,126 conditions by eHealthMe. Check the latest studies of Depression.



On Jul, 23, 2026

9,755 people reported to have side effects when taking Arixtra.
Among them, 28 people (0.29%) have Depression.

Could Arixtra cause Depression?

Among these 28 people:

How long have people been on Arixtra when they have Depression? *

  • < 1 month: 60 %
  • 1 - 6 months: 40 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Depression when taking Arixtra? *

  • female: 73.68 %
  • male: 26.32 %

What is the age of people who have Depression when taking Arixtra? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 23.53 %
  • 50-59: 23.53 %
  • 60+: 52.94 %

What are other drugs people take besides Arixtra? *

  1. Dilaudid: 12 people, 42.86%
  2. Lovenox: 10 people, 35.71%
  3. Xanax: 9 people, 32.14%
  4. Lasix: 9 people, 32.14%
  5. Benicar: 8 people, 28.57%
  6. Pantoprazole: 8 people, 28.57%
  7. Pepcid: 8 people, 28.57%
  8. Jakafi: 8 people, 28.57%
  9. Aspirin: 6 people, 21.43%
  10. Astelin: 5 people, 17.86%

What are other side effects people have besides Depression? *

  1. High Blood Pressure: 14 people, 50.00%
  2. Stress And Anxiety: 14 people, 50.00%
  3. Anaemia (lack of blood): 13 people, 46.43%
  4. Fatigue (feeling of tiredness): 13 people, 46.43%
  5. Nausea (feeling of having an urge to vomit): 13 people, 46.43%
  6. Abdominal Pain: 12 people, 42.86%
  7. Joint Pain: 12 people, 42.86%
  8. Red Blood Cell Count Decreased: 11 people, 39.29%
  9. Fall: 11 people, 39.29%
  10. Gait Disturbance: 11 people, 39.29%

What are the existing conditions these people have? *

  1. Primary Myelofibrosis (primary disorder of the bone marrow): 8 people, 28.57%
  2. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 8 people, 28.57%
  3. Breast Cancer Female: 3 people, 10.71%
  4. Pain: 3 people, 10.71%
  5. Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 7.14%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 7.14%
  7. Stress And Anxiety: 2 people, 7.14%
  8. High Blood Pressure: 2 people, 7.14%
  9. High Blood Cholesterol: 2 people, 7.14%
  10. Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Arixtra and have Depression?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arixtra:

Depression treatments and more:

How severe was Depression and when was it recovered:

Expand to all the drugs that have ingredients of fondaparinux sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arixtra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression:

Browse all the conditions that are associated with Depression:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fondaparinux sodium (the active ingredients of Arixtra) and Arixtra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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