Arixtra and Scleroma - a phase IV clinical study of FDA data

Summary:

Scleroma is reported as a side effect among people who take Arixtra (fondaparinux sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Scleroma when taking Arixtra. It is created by eHealthMe based on reports of 9,755 people who have side effects when taking Arixtra from the FDA, and is updated regularly.

What is Arixtra?

Arixtra has active ingredients of fondaparinux sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 9,830 Arixtra users. Check the latest studies of Arixtra.

What is Scleroma?

Scleroma (a hardened patch of tissue in the skin or mucous membranes) is found to be associated with 308 drugs and 490 conditions by eHealthMe. Check the latest studies of Scleroma.

On Jul, 14, 2026

9,755 people reported to have side effects when taking Arixtra.
Among them, 21 people (0.22%) have Scleroma.

Among these 21 people:

How long have people been on Arixtra when they have Scleroma? *

What is the gender of people who have Scleroma when taking Arixtra? *

female: 35 %
male: 65 %

What is the age of people who have Scleroma when taking Arixtra? *

What are other drugs people take besides Arixtra? *

What are other side effects people have besides Scleroma? *

Haematoma (collection of blood outside the blood vessels): 11 people, 52.38%
Anaemia (lack of blood): 7 people, 33.33%
Haemoglobin Decreased: 6 people, 28.57%
Abdominal Pain: 4 people, 19.05%
Oedema Peripheral (superficial swelling): 4 people, 19.05%
Thrombocytopenia (decrease of platelets in blood): 3 people, 14.29%
Prothrombin Level Decreased: 3 people, 14.29%
Muscle Haemorrhage (bleeding in muscle): 3 people, 14.29%
Aspartate Aminotransferase Increased: 2 people, 9.52%
Back Pain: 2 people, 9.52%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 23.81%
Type 2 Diabetes: 1 person, 4.76%
Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 4.76%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 4.76%
Erysipelas (bacterial skin infection): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Arixtra and have Scleroma?

- Check whether Scleroma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arixtra:

Arixtra (9,830 reports)

Scleroma treatments and more:

Scleroma (2,214 reports)

Browse all side effects of Arixtra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Scleroma:

Scleroma (308 drugs)

Browse all the conditions that are associated with Scleroma:

Scleroma (490 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fondaparinux sodium (the active ingredients of Arixtra) and Arixtra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.