Armour thyroid and Middle insomnia - a phase IV clinical study of FDA data

Summary:

Middle insomnia is reported as a side effect among people who take Armour thyroid (thyroid tablets, usp), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Singulair, and have Pain.

The phase IV clinical study analyzes which people have Middle insomnia when taking Armour thyroid. It is created by eHealthMe based on reports of 10,921 people who have side effects when taking Armour thyroid from the FDA, and is updated regularly.

What is Armour thyroid?

Armour thyroid has active ingredients of thyroid tablets, usp. It is often used in hypothyroidism. eHealthMe is studying from 11,975 Armour thyroid users. Check the latest studies of Armour thyroid.

What is Middle insomnia?

Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night) is found to be associated with 985 drugs and 971 conditions by eHealthMe. Check the latest studies of Middle insomnia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

10,921 people reported to have side effects when taking Armour thyroid.
Among them, 32 people (0.29%) have Middle insomnia.

Could Armour thyroid cause Middle insomnia?

Among these 32 people:

How long have people been on Armour thyroid when they have Middle insomnia? *

What is the gender of people who have Middle insomnia when taking Armour thyroid? *

female: 93.55 %
male: 6.45 %

What is the age of people who have Middle insomnia when taking Armour thyroid? *

What are other drugs people take besides Armour thyroid? *

What are other side effects people have besides Middle insomnia? *

Insomnia (sleeplessness): 10 people, 31.25%
Joint Pain: 7 people, 21.88%
Pain: 7 people, 21.88%
Headache (pain in head): 6 people, 18.75%
Feeling Jittery: 5 people, 15.62%
Weakness: 5 people, 15.62%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 12.50%
Muscle Aches (muscle pain): 4 people, 12.50%
Drowsiness: 4 people, 12.50%
Stress And Anxiety: 4 people, 12.50%

What are the existing conditions these people have? *

Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 15.62%
Pain: 5 people, 15.62%
Spinal Cord Trauma: 4 people, 12.50%
Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 4 people, 12.50%
Pain In Extremity: 4 people, 12.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 12.50%
Insomnia (sleeplessness): 3 people, 9.38%
Neuralgia (pain in one or more nerves): 2 people, 6.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 6.25%
Back Pain: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Armour thyroid and have Middle insomnia?

- Check whether Middle insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Armour thyroid:

Armour thyroid (11,975 reports)

Middle insomnia treatments and more:

Middle insomnia (21,952 reports)

Browse all side effects of Armour thyroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Middle insomnia:

Middle insomnia (985 drugs)

Browse all the conditions that are associated with Middle insomnia:

Middle insomnia (971 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on thyroid tablets, usp (the active ingredients of Armour thyroid) and Armour thyroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.