Artane and Muscle spasms - a phase IV clinical study of FDA data

Summary:

Muscle spasms is reported as a side effect among people who take Artane (trihexyphenidyl hydrochloride), especially for people who are male, 40-49 old, also take Abilify, and have Depression.

The phase IV clinical study analyzes which people have Muscle spasms when taking Artane. It is created by eHealthMe based on reports of 3,524 people who have side effects when taking Artane from the FDA, and is updated regularly.

What is Artane?

Artane has active ingredients of trihexyphenidyl hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 3,619 Artane users. Check the latest studies of Artane.

What is Muscle spasms?

Muscle spasms (muscle contraction) is found to be associated with 2,675 drugs and 3,100 conditions by eHealthMe. Check the latest studies of Muscle spasms.



On Jul, 23, 2026

3,524 people reported to have side effects when taking Artane.
Among them, 27 people (0.77%) have Muscle spasms.

Could Artane cause Muscle spasms?

Among these 27 people:

What is the gender of people who have Muscle spasms when taking Artane? *

  • female: 40 %
  • male: 60 %

What is the age of people who have Muscle spasms when taking Artane? *

  • 0-1: 0.0 %
  • 2-9: 9.52 %
  • 10-19: 0.0 %
  • 20-29: 4.76 %
  • 30-39: 9.52 %
  • 40-49: 38.1 %
  • 50-59: 9.52 %
  • 60+: 28.57 %

What are other drugs people take besides Artane? *

  1. Zyprexa: 4 people, 14.81%
  2. Sinemet: 4 people, 14.81%
  3. Clonidine: 4 people, 14.81%
  4. Lisinopril: 4 people, 14.81%
  5. Neurontin: 4 people, 14.81%
  6. Paxil: 4 people, 14.81%
  7. Requip: 4 people, 14.81%
  8. Risperdal: 4 people, 14.81%
  9. Abilify: 4 people, 14.81%
  10. Baclofen: 3 people, 11.11%

What are other side effects people have besides Muscle spasms? *

  1. Dizziness: 12 people, 44.44%
  2. Pain In Extremity: 10 people, 37.04%
  3. Memory Loss: 9 people, 33.33%
  4. Dyskinesia (abnormality or impairment of voluntary movement): 9 people, 33.33%
  5. Stress And Anxiety: 9 people, 33.33%
  6. Head Injury: 8 people, 29.63%
  7. Headache (pain in head): 8 people, 29.63%
  8. Fall: 8 people, 29.63%
  9. Depression: 8 people, 29.63%
  10. Gait Disturbance: 7 people, 25.93%

What are the existing conditions these people have? *

  1. Abnormal Faeces (abnormal stool): 4 people, 14.81%
  2. Bipolar Disorder (mood disorder): 4 people, 14.81%
  3. Depression: 4 people, 14.81%
  4. Stress And Anxiety: 2 people, 7.41%
  5. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 7.41%
  6. Nausea (feeling of having an urge to vomit): 2 people, 7.41%
  7. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 7.41%
  8. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 1 person, 3.70%
  9. Affective Disorder (mental disorder): 1 person, 3.70%
  10. Borderline Personality Disorder: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Artane and have Muscle spasms?

- Check whether Muscle spasms is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Artane:

Muscle spasms treatments and more:

How severe was Muscle spasms and when was it recovered:

Expand to all the drugs that have ingredients of trihexyphenidyl hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Artane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle spasms:

Browse all the conditions that are associated with Muscle spasms:


How the study uses the data?

The study uses data from the FDA. It is based on trihexyphenidyl hydrochloride (the active ingredients of Artane) and Artane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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