Artane and Overdose - a phase IV clinical study of FDA data

Summary:

Overdose is reported as a side effect among people who take Artane (trihexyphenidyl hydrochloride), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Valium, and have Back pain.

The phase IV clinical study analyzes which people have Overdose when taking Artane. It is created by eHealthMe based on reports of 3,524 people who have side effects when taking Artane from the FDA, and is updated regularly.

What is Artane?

Artane has active ingredients of trihexyphenidyl hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 3,619 Artane users. Check the latest studies of Artane.

What is Overdose?

Overdose is found to be associated with 2,220 drugs and 2,471 conditions by eHealthMe. Check the latest studies of Overdose.



On Jul, 10, 2026

3,524 people reported to have side effects when taking Artane.
Among them, 75 people (2.13%) have Overdose.

Could Artane cause Overdose?

Among these 75 people:

How long have people been on Artane when they have Overdose? *

  • < 1 month: 50 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 25 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Overdose when taking Artane? *

  • female: 40.28 %
  • male: 59.72 %

What is the age of people who have Overdose when taking Artane? *

  • 0-1: 0.0 %
  • 2-9: 7.14 %
  • 10-19: 0.0 %
  • 20-29: 8.57 %
  • 30-39: 27.14 %
  • 40-49: 21.43 %
  • 50-59: 10.0 %
  • 60+: 25.71 %

What are other drugs people take besides Artane? *

  1. Valium: 14 people, 18.67%
  2. Oxycontin: 12 people, 16.00%
  3. Zyprexa: 10 people, 13.33%
  4. Prazepam: 8 people, 10.67%
  5. Tegretol: 8 people, 10.67%
  6. Fentanyl: 8 people, 10.67%
  7. Clobazam: 8 people, 10.67%
  8. Quetiapine Fumarate: 8 people, 10.67%
  9. Seroquel: 7 people, 9.33%
  10. Paroxetine Mesylate: 7 people, 9.33%

What are other side effects people have besides Overdose? *

  1. Accidental Poisoning: 12 people, 16.00%
  2. Heart Attack: 12 people, 16.00%
  3. Respiratory Depression (respiration has a rate below 12 breaths): 12 people, 16.00%
  4. Drowsiness: 10 people, 13.33%
  5. Hallucinations (sensations that appear real but are created by your mind): 8 people, 10.67%
  6. Consciousness - Decreased: 8 people, 10.67%
  7. Suicide Attempt: 8 people, 10.67%
  8. Hepatitis Acute: 7 people, 9.33%
  9. Encephalopathy (functioning of the brain is affected by some agent or condition): 7 people, 9.33%
  10. Cardiomyopathy (weakening of the heart muscle): 7 people, 9.33%

What are the existing conditions these people have? *

  1. Back Pain: 12 people, 16.00%
  2. Depression: 10 people, 13.33%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 6.67%
  4. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 6.67%
  5. Pain: 3 people, 4.00%
  6. Nausea (feeling of having an urge to vomit): 2 people, 2.67%
  7. Stress And Anxiety: 2 people, 2.67%
  8. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 2.67%
  9. Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2 people, 2.67%
  10. Tardive Dyskinesia (a disorder that involves involuntary movements): 1 person, 1.33%

* Approximation only. Some reports may have incomplete information.

Do you take Artane and have Overdose?

- Check whether Overdose is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Artane:

Overdose treatments and more:

How severe was Overdose and when was it recovered:

Expand to all the drugs that have ingredients of trihexyphenidyl hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Artane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Overdose:

Browse all the conditions that are associated with Overdose:


How the study uses the data?

The study uses data from the FDA. It is based on trihexyphenidyl hydrochloride (the active ingredients of Artane) and Artane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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