Artane and Pollakiuria - a phase IV clinical study of FDA data

Summary:

Pollakiuria is reported as a side effect among people who take Artane (trihexyphenidyl hydrochloride), especially for people who are male, 60+ old, also take Depakote, and have Schizophrenia.

The phase IV clinical study analyzes which people have Pollakiuria when taking Artane. It is created by eHealthMe based on reports of 3,524 people who have side effects when taking Artane from the FDA, and is updated regularly.

What is Artane?

Artane has active ingredients of trihexyphenidyl hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 3,619 Artane users. Check the latest studies of Artane.

What is Pollakiuria?

Pollakiuria (abnormally frequent passage of relatively small quantities or urine) is found to be associated with 1,749 drugs and 1,692 conditions by eHealthMe. Check the latest studies of Pollakiuria.



On Jul, 06, 2026

3,524 people reported to have side effects when taking Artane.
Among them, 18 people (0.51%) have Pollakiuria.

Could Artane cause Pollakiuria?

Among these 18 people:

What is the gender of people who have Pollakiuria when taking Artane? *

  • female: 38.89 %
  • male: 61.11 %

What is the age of people who have Pollakiuria when taking Artane? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 15.38 %
  • 40-49: 23.08 %
  • 50-59: 15.38 %
  • 60+: 46.15 %

What are other drugs people take besides Artane? *

  1. Risperdal: 7 people, 38.89%
  2. Depakote: 7 people, 38.89%
  3. Clozaril: 6 people, 33.33%
  4. Cogentin: 5 people, 27.78%
  5. Haldol: 5 people, 27.78%
  6. Zyprexa: 3 people, 16.67%
  7. Paxil: 3 people, 16.67%
  8. Tamsulosin: 3 people, 16.67%
  9. Requip: 3 people, 16.67%
  10. Prevacid: 3 people, 16.67%

What are other side effects people have besides Pollakiuria? *

  1. Constipation: 11 people, 61.11%
  2. Fall: 10 people, 55.56%
  3. Gait Disturbance: 9 people, 50.00%
  4. Dizziness: 8 people, 44.44%
  5. Fatigue (feeling of tiredness): 8 people, 44.44%
  6. Headache (pain in head): 7 people, 38.89%
  7. Nausea (feeling of having an urge to vomit): 7 people, 38.89%
  8. Psychotic Disorder: 6 people, 33.33%
  9. Abnormal Behavior: 6 people, 33.33%
  10. Depression: 6 people, 33.33%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 22.22%
  2. Abnormal Faeces (abnormal stool): 3 people, 16.67%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.56%
  4. Psychotic Disorder: 1 person, 5.56%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 5.56%
  6. Pain: 1 person, 5.56%
  7. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 1 person, 5.56%
  8. High Blood Cholesterol: 1 person, 5.56%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.56%
  10. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Artane and have Pollakiuria?

- Check whether Pollakiuria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Artane:

Pollakiuria treatments and more:

How severe was Pollakiuria and when was it recovered:

Expand to all the drugs that have ingredients of trihexyphenidyl hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Artane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pollakiuria:

Browse all the conditions that are associated with Pollakiuria:


How the study uses the data?

The study uses data from the FDA. It is based on trihexyphenidyl hydrochloride (the active ingredients of Artane) and Artane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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