Arthrotec and Paleness - a phase IV clinical study of FDA data

Summary:

Paleness is reported as a side effect among people who take Arthrotec (diclofenac sodium; misoprostol), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Sertraline, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Paleness when taking Arthrotec. It is created by eHealthMe based on reports of 11,570 people who have side effects when taking Arthrotec from the FDA, and is updated regularly.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.

What is Paleness?

Paleness (unusual lightness of skin colour) is found to be associated with 1,564 drugs and 2,117 conditions by eHealthMe. Check the latest studies of Paleness.

On Jul, 09, 2026

11,570 people reported to have side effects when taking Arthrotec.
Among them, 31 people (0.27%) have Paleness.

Among these 31 people:

How long have people been on Arthrotec when they have Paleness? *

What is the gender of people who have Paleness when taking Arthrotec? *

female: 67.74 %
male: 32.26 %

What is the age of people who have Paleness when taking Arthrotec? *

What are other drugs people take besides Arthrotec? *

What are other side effects people have besides Paleness? *

Nausea (feeling of having an urge to vomit): 15 people, 48.39%
Fatigue (feeling of tiredness): 13 people, 41.94%
Weakness: 12 people, 38.71%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 10 people, 32.26%
Joint Pain: 10 people, 32.26%
Fever: 10 people, 32.26%
Speech Impairment (Adult) (inability to speak (adult)): 9 people, 29.03%
Diarrhea: 9 people, 29.03%
Dyspnea (difficult or laboured breathing): 9 people, 29.03%
Abdominal Pain: 8 people, 25.81%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 22.58%
Toothaches (tooth pain): 3 people, 9.68%
Dysmenorrhea (painful menstruation): 3 people, 9.68%
Asthma: 3 people, 9.68%
Prostate Cancer: 3 people, 9.68%
Stress And Anxiety: 3 people, 9.68%
Gastrointestinal Pain: 3 people, 9.68%
Prostate Cancer Metastatic: 2 people, 6.45%
Birth Control: 1 person, 3.23%
Cardiac Disorder: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Arthrotec and have Paleness?

- Check whether Paleness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arthrotec:

Arthrotec (11,986 reports)

Paleness treatments and more:

Paleness (34,670 reports)

How severe was Paleness and when was it recovered:

Paleness in Arthrotec

Expand to all the drugs that have ingredients of diclofenac sodium; misoprostol:

Paleness and drugs with ingredients of diclofenac sodium; misoprostol

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arthrotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Paleness:

Paleness (1,564 drugs)

Browse all the conditions that are associated with Paleness:

Paleness (2,117 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium; misoprostol (the active ingredients of Arthrotec) and Arthrotec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.