Ascorbate and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Ascorbate (vitamin c (ascorbic acid)), especially for people who are female, 60+ old, also take Biotin, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Ascorbate. It is created by eHealthMe based on reports of 1,412 people who have side effects when taking Ascorbate from the FDA, and is updated regularly.

What is Ascorbate?

Ascorbate has active ingredients of vitamin c (ascorbic acid). eHealthMe is studying from 1,446 Ascorbate users. Check the latest studies of Ascorbate.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,959 drugs and 2,936 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

On Jun, 22, 2026

1,412 people reported to have side effects when taking Ascorbate.
Among them, 74 people (5.24%) have Hyperkalemia.

Among these 74 people:

What is the gender of people who have Hyperkalemia when taking Ascorbate? *

female: 100 %
male: 0.0 %

What is the age of people who have Hyperkalemia when taking Ascorbate? *

What are other drugs people take besides Ascorbate? *

What are other side effects people have besides Hyperkalemia? *

Nausea (feeling of having an urge to vomit): 73 people, 98.65%
Dry Eyes (lack of adequate tears): 72 people, 97.30%
Osteopenia (a condition where bone mineral density is lower than normal): 72 people, 97.30%
Diarrhea: 72 people, 97.30%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 72 people, 97.30%
Deafness Neurosensory: 72 people, 97.30%
Cyst (a closed sac): 72 people, 97.30%
Epigastric Discomfort: 72 people, 97.30%
Drug Intolerance (drug sensitivity): 72 people, 97.30%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 72 people, 97.30%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 72 people, 97.30%
Sleep Disorder: 63 people, 85.14%
Pain: 55 people, 74.32%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 48 people, 64.86%
Adenomatous Polyposis Coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine): 36 people, 48.65%
Dry Eyes (lack of adequate tears): 33 people, 44.59%
Multiple Myeloma (cancer of the plasma cells): 1 person, 1.35%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 1.35%
High Blood Cholesterol: 1 person, 1.35%

* Approximation only. Some reports may have incomplete information.

Do you take Ascorbate and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ascorbate:

Ascorbate (1,446 reports)

Hyperkalemia treatments and more:

Hyperkalemia (78,084 reports)

Browse all side effects of Ascorbate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Hyperkalemia (1,959 drugs)

Browse all the conditions that are associated with Hyperkalemia:

Hyperkalemia (2,936 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on vitamin c (ascorbic acid) (the active ingredients of Ascorbate) and Ascorbate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.