Astelin and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is reported as a side effect among people who take Astelin (azelastine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Flonase, and have Osteoporosis.

The phase IV clinical study analyzes which people have Joint swelling when taking Astelin. It is created by eHealthMe based on reports of 5,326 people who have side effects when taking Astelin from the FDA, and is updated regularly.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

What is Joint swelling?

Joint swelling is found to be associated with 2,120 drugs and 2,934 conditions by eHealthMe. Check the latest studies of Joint swelling.



On Jul, 14, 2026

5,326 people reported to have side effects when taking Astelin.
Among them, 94 people (1.76%) have Joint swelling.

Could Astelin cause Joint swelling?

Among these 94 people:

How long have people been on Astelin when they have Joint swelling? *

  • < 1 month: 25 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 25 %
  • 10+ years: 0.0 %

What is the gender of people who have Joint swelling when taking Astelin? *

  • female: 93.98 %
  • male: 6.02 %

What is the age of people who have Joint swelling when taking Astelin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.61 %
  • 20-29: 0.0 %
  • 30-39: 1.61 %
  • 40-49: 8.06 %
  • 50-59: 22.58 %
  • 60+: 66.13 %

What are other drugs people take besides Astelin? *

  1. Flonase: 40 people, 42.55%
  2. Xanax: 38 people, 40.43%
  3. Zometa: 37 people, 39.36%
  4. Protonix: 37 people, 39.36%
  5. Lasix: 35 people, 37.23%
  6. Mirtazapine: 35 people, 37.23%
  7. Celexa: 35 people, 37.23%
  8. Albuterol: 32 people, 34.04%
  9. Synthroid: 32 people, 34.04%
  10. Aspirin: 31 people, 32.98%

What are other side effects people have besides Joint swelling? *

  1. Fatigue (feeling of tiredness): 55 people, 58.51%
  2. Pain: 52 people, 55.32%
  3. Stress And Anxiety: 52 people, 55.32%
  4. Joint Pain: 50 people, 53.19%
  5. Balance Disorder: 45 people, 47.87%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 42 people, 44.68%
  7. Weakness: 42 people, 44.68%
  8. Dyspnea (difficult or laboured breathing): 41 people, 43.62%
  9. Depression: 40 people, 42.55%
  10. Dizziness: 40 people, 42.55%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 25 people, 26.60%
  2. Calcium Deficiency (lack of calcium): 24 people, 25.53%
  3. Neoplasm Malignant (cancer tumour): 24 people, 25.53%
  4. Metastases To Spine (cancer spreads to spine): 24 people, 25.53%
  5. Lung Neoplasm (tumour of lung): 23 people, 24.47%
  6. Hypersensitivity: 10 people, 10.64%
  7. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 9 people, 9.57%
  8. Primary Myelofibrosis (primary disorder of the bone marrow): 9 people, 9.57%
  9. Asthma: 8 people, 8.51%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 8.51%

* Approximation only. Some reports may have incomplete information.

Do you take Astelin and have Joint swelling?

- Check whether Joint swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Astelin:

Joint swelling treatments and more:

How severe was Joint swelling and when was it recovered:

Expand to all the drugs that have ingredients of azelastine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Astelin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint swelling:

Browse all the conditions that are associated with Joint swelling:


How the study uses the data?

The study uses data from the FDA. It is based on azelastine hydrochloride (the active ingredients of Astelin) and Astelin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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