Astelin and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Astelin (azelastine hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Aspirin, and have Osteoporosis.

The phase IV clinical study analyzes which people have Sciatica when taking Astelin. It is created by eHealthMe based on reports of 5,326 people who have side effects when taking Astelin from the FDA, and is updated regularly.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,146 drugs and 1,427 conditions by eHealthMe. Check the latest studies of Sciatica.

On Feb, 27, 2026

5,326 people reported to have side effects when taking Astelin.
Among them, 18 people (0.34%) have Sciatica.

Among these 18 people:

How long have people been on Astelin when they have Sciatica? *

What is the gender of people who have Sciatica when taking Astelin? *

female: 94.12 %
male: 5.88 %

What is the age of people who have Sciatica when taking Astelin? *

What are other drugs people take besides Astelin? *

What are other side effects people have besides Sciatica? *

Pain: 15 people, 83.33%
Pain In Extremity: 15 people, 83.33%
Fall: 14 people, 77.78%
Stress And Anxiety: 14 people, 77.78%
Abdominal Pain Upper: 13 people, 72.22%
Spinal Osteoarthritis (joint cartilage loss in spine): 13 people, 72.22%
Foot Fracture: 13 people, 72.22%
Injury: 13 people, 72.22%
Dizziness: 13 people, 72.22%
Joint Swelling: 13 people, 72.22%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 14 people, 77.78%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 11.11%
Stress And Anxiety: 1 person, 5.56%
Post-Traumatic Stress Disorder: 1 person, 5.56%
Muscle Spasms (muscle contraction): 1 person, 5.56%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.56%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 5.56%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 5.56%
Hypersensitivity: 1 person, 5.56%
High Blood Pressure: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Astelin and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Astelin:

Astelin (5,538 reports)

Sciatica treatments and more:

Sciatica (28,509 reports)

Browse all side effects of Astelin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,146 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,427 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on azelastine hydrochloride (the active ingredients of Astelin) and Astelin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.