Atarax and Hyperpathia - a phase IV clinical study of FDA data

Summary:

Hyperpathia is reported as a side effect among people who take Atarax (hydroxyzine hydrochloride), especially for people who are female, 60+ old, also take Norvasc, and have Pain.

The phase IV clinical study analyzes which people have Hyperpathia when taking Atarax. It is created by eHealthMe based on reports of 22,841 people who have side effects when taking Atarax from the FDA, and is updated regularly.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

What is Hyperpathia?

Hyperpathia (clinical symptom of certain neurological disorders wherein nociceptive stimuli evoke exaggerated levels of pain) is found to be associated with 25 drugs and 18 conditions by eHealthMe. Check the latest studies of Hyperpathia.



On Jun, 12, 2026

22,841 people reported to have side effects when taking Atarax.
Among them, 15 people (0.07%) have Hyperpathia.

Could Atarax cause Hyperpathia?

Among these 15 people:

What is the gender of people who have Hyperpathia when taking Atarax? *

  • female: 93.33 %
  • male: 6.67 %

What is the age of people who have Hyperpathia when taking Atarax? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 33.33 %
  • 60+: 66.67 %

What are other drugs people take besides Atarax? *

  1. Norvasc: 14 people, 93.33%
  2. Dilaudid: 13 people, 86.67%
  3. Fentanyl: 11 people, 73.33%
  4. Evista: 9 people, 60.00%
  5. Neurontin: 9 people, 60.00%
  6. Lasix: 9 people, 60.00%
  7. Gabapentin: 9 people, 60.00%
  8. Fosamax: 9 people, 60.00%
  9. Folic Acid: 9 people, 60.00%
  10. Zocor: 9 people, 60.00%

What are other side effects people have besides Hyperpathia? *

  1. Weakness: 15 people, 100.00%
  2. Anaemia (lack of blood): 15 people, 100.00%
  3. Nausea (feeling of having an urge to vomit): 15 people, 100.00%
  4. Back Pain: 15 people, 100.00%
  5. Intervertebral Disc Degeneration (spinal disc degeneration): 15 people, 100.00%
  6. Osteomyelitis (infection of bone): 15 people, 100.00%
  7. Pain In Extremity: 15 people, 100.00%
  8. Headache (pain in head): 15 people, 100.00%
  9. Fever: 14 people, 93.33%
  10. Purulent Discharge (discharge that contains pus): 14 people, 93.33%

What are the existing conditions these people have? *

  1. Pain: 6 people, 40.00%
  2. Tremor (trembling or shaking movements in one or more parts of your body): 5 people, 33.33%
  3. Neuralgia (pain in one or more nerves): 4 people, 26.67%
  4. Paranasal Sinus Hypersecretion: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Atarax and have Hyperpathia?

- Check whether Hyperpathia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Atarax:

Hyperpathia treatments and more:

How severe was Hyperpathia and when was it recovered:

Expand to all the drugs that have ingredients of hydroxyzine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperpathia:

Browse all the conditions that are associated with Hyperpathia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Atarax) and Atarax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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