Atenolol and Hyperosmolar state - a phase IV clinical study of FDA data

Summary:

Hyperosmolar state is reported as a side effect among people who take Atenolol (atenolol), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lortab, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Hyperosmolar state when taking Atenolol. It is created by eHealthMe based on reports of 170,420 people who have side effects when taking Atenolol from the FDA, and is updated regularly.

What is Atenolol?

Atenolol has active ingredients of atenolol. It is often used in high blood pressure. eHealthMe is studying from 176,618 Atenolol users. Check the latest studies of Atenolol.

What is Hyperosmolar state?

Hyperosmolar state (life-threatening emergency manifested by marked elevation of blood glucose) is found to be associated with 69 drugs and 258 conditions by eHealthMe. Check the latest studies of Hyperosmolar state.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

170,420 people reported to have side effects when taking Atenolol.
Among them, 12 people (0.01%) have Hyperosmolar state.

Could Atenolol cause Hyperosmolar state?

Among these 12 people:

How long have people been on Atenolol when they have Hyperosmolar state? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperosmolar state when taking Atenolol? *

  • female: 75 %
  • male: 25 %

What is the age of people who have Hyperosmolar state when taking Atenolol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 18.18 %
  • 40-49: 27.27 %
  • 50-59: 0.0 %
  • 60+: 54.55 %

What are other drugs people take besides Atenolol? *

  1. Lisinopril: 4 people, 33.33%
  2. Lasix: 4 people, 33.33%
  3. Lortab: 4 people, 33.33%
  4. Acetaminophen: 3 people, 25.00%
  5. Celexa: 3 people, 25.00%
  6. Metoprolol Tartrate: 3 people, 25.00%
  7. Zyprexa: 3 people, 25.00%
  8. Morphine Sulfate: 3 people, 25.00%
  9. Lantus: 3 people, 25.00%
  10. Ipratropium Bromide: 3 people, 25.00%

What are other side effects people have besides Hyperosmolar state? *

  1. Diabetes: 5 people, 41.67%
  2. Ileus Paralytic (obstruction of the intestine due to paralysis of the intestinal muscles): 4 people, 33.33%
  3. Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 33.33%
  4. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 4 people, 33.33%
  5. Stress And Anxiety: 4 people, 33.33%
  6. Weight Increased: 3 people, 25.00%
  7. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 25.00%
  8. Hypotension (abnormally low blood pressure): 3 people, 25.00%
  9. Weight Decreased: 3 people, 25.00%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 25.00%

What are the existing conditions these people have? *

  1. Bipolar Disorder (mood disorder): 3 people, 25.00%
  2. Pain: 2 people, 16.67%
  3. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 16.67%
  4. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 16.67%
  5. Pharyngitis (inflammation of the pharynx, causing a sore throat): 1 person, 8.33%
  6. Headache (pain in head): 1 person, 8.33%
  7. Acute Psychosis (period of mentally unstable behaviour): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Atenolol and have Hyperosmolar state?

- Check whether Hyperosmolar state is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Atenolol:

Hyperosmolar state treatments and more:

How severe was Hyperosmolar state and when was it recovered:

Expand to all the drugs that have ingredients of atenolol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Atenolol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperosmolar state:

Browse all the conditions that are associated with Hyperosmolar state:


How the study uses the data?

The study uses data from the FDA. It is based on atenolol (the active ingredients of Atenolol) and Atenolol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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