Ativan and Narcolepsy - a phase IV clinical study of FDA data
Summary:
Narcolepsy is reported as a side effect among people who take Ativan (lorazepam), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Omeprazole, and have Nausea.
The phase IV clinical study analyzes which people have Narcolepsy when taking Ativan. It is created by eHealthMe based on reports of 74,376 people who have side effects when taking Ativan from the FDA, and is updated regularly.
What is Ativan?
Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 78,506 Ativan users. Check the latest studies of Ativan.
What is Narcolepsy?
Narcolepsy (brain's inability to regulate sleep-wake cycles normally) is found to be associated with 422 drugs and 740 conditions by eHealthMe. Check the latest studies of Narcolepsy.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
74,376 people reported to have side effects when taking Ativan.
Among them, 36 people (0.05%) have Narcolepsy.

Among these 36 people:
How long have people been on Ativan when they have Narcolepsy? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 100 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Narcolepsy when taking Ativan? *
- female: 61.76 %
- male: 38.24 %
What is the age of people who have Narcolepsy when taking Ativan? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 12 %
- 30-39: 0.0 %
- 40-49: 32 %
- 50-59: 52 %
- 60+: 4 %
What are other drugs people take besides Ativan? *
- Omeprazole: 12 people, 33.33%
- Prilosec: 11 people, 30.56%
- Ibuprofen: 10 people, 27.78%
- Levaquin: 10 people, 27.78%
- Vioxx: 10 people, 27.78%
- Skelaxin: 9 people, 25.00%
- Premarin: 9 people, 25.00%
- Hydrocortisone: 8 people, 22.22%
- Modafinil: 8 people, 22.22%
- Celebrex: 7 people, 19.44%
What are other side effects people have besides Narcolepsy? *
- Hypoaesthesia (reduced sense of touch or sensation): 15 people, 41.67%
- Depression: 13 people, 36.11%
- Weakness: 12 people, 33.33%
- Constipation: 11 people, 30.56%
- Chest Pain: 11 people, 30.56%
- Muscle Aches (muscle pain): 10 people, 27.78%
- Dyspnea (difficult or laboured breathing): 10 people, 27.78%
- Joint Pain: 10 people, 27.78%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 25.00%
- Drowsiness: 9 people, 25.00%
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 6 people, 16.67%
- Prostate Cancer: 5 people, 13.89%
- Metastases To Bone (cancer spreads to bone): 5 people, 13.89%
- Belching (release of gas from the digestive tract): 4 people, 11.11%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 11.11%
- Panic Disorder: 3 people, 8.33%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 8.33%
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 5.56%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.56%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Ativan and have Narcolepsy?
- Check whether Narcolepsy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Ativan:
- Ativan (78,506 reports)
Narcolepsy treatments and more:
- Narcolepsy (79,890 reports)
How severe was Narcolepsy and when was it recovered:
Expand to all the drugs that have ingredients of lorazepam:
- Narcolepsy and drugs with ingredients of lorazepam (72 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ativan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Narcolepsy:
- Narcolepsy (422 drugs)
Browse all the conditions that are associated with Narcolepsy:
- Narcolepsy (740 conditions)
Related publications that referenced our studies
- Han SH, Lee SA, "Superficial Vein Thrombosis as the Initial Manifestation of Protein S Deficiency in an Adolescent with Narcolepsy", Sleep Medicine Research, 2016 Jun .
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
- Han SH, Lee SA, "Superficial Vein Thrombosis as the Initial Manifestation of Protein S Deficiency in an Adolescent with Narcolepsy", Sleep Medicine Research, 2016 Jun .
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on lorazepam (the active ingredients of Ativan) and Ativan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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