Ativan and Optic neuropathy - a phase IV clinical study of FDA data
Summary:
Optic neuropathy is reported as a side effect among people who take Ativan (lorazepam), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Celexa, and have Pancreatic carcinoma.
The phase IV clinical study analyzes which people have Optic neuropathy when taking Ativan. It is created by eHealthMe based on reports of 74,376 people who have side effects when taking Ativan from the FDA, and is updated regularly.
What is Ativan?
Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 78,506 Ativan users. Check the latest studies of Ativan.
What is Optic neuropathy?
Optic neuropathy (optic nerve damage) is found to be associated with 258 drugs and 451 conditions by eHealthMe. Check the latest studies of Optic neuropathy.
74,376 people reported to have side effects when taking Ativan.
Among them, 25 people (0.03%) have Optic neuropathy.

Among these 25 people:
How long have people been on Ativan when they have Optic neuropathy? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 100 %
- 10+ years: 0.0 %
What is the gender of people who have Optic neuropathy when taking Ativan? *
- female: 48 %
- male: 52 %
What is the age of people who have Optic neuropathy when taking Ativan? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 9.52 %
- 40-49: 14.29 %
- 50-59: 14.29 %
- 60+: 61.9 %
What are other drugs people take besides Ativan? *
- Motrin: 7 people, 28.00%
- Vicodin: 7 people, 28.00%
- Celexa: 7 people, 28.00%
- Compazine: 6 people, 24.00%
- Lipitor: 6 people, 24.00%
- Lovastatin: 5 people, 20.00%
- Oxycontin: 5 people, 20.00%
- Metoclopramide: 5 people, 20.00%
- Miralax: 5 people, 20.00%
- Ambien: 5 people, 20.00%
What are other side effects people have besides Optic neuropathy? *
- Papilloedema (optic disc swelling): 5 people, 20.00%
- Cataract (clouding of the lens inside the eye): 5 people, 20.00%
- Vision Blurred: 5 people, 20.00%
- Headache (pain in head): 4 people, 16.00%
- Rashes (redness): 4 people, 16.00%
- Optic Atrophy (the loss of a proportion of optic disc nerve fibres): 4 people, 16.00%
- Depression: 4 people, 16.00%
- Diarrhea: 4 people, 16.00%
- Nausea (feeling of having an urge to vomit): 4 people, 16.00%
- Indigestion: 3 people, 12.00%
What are the existing conditions these people have? *
- Pancreatic Carcinoma (pancreatic cancer): 5 people, 20.00%
- Depression: 4 people, 16.00%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 16.00%
- Lung Cancer - Non-Small Cell (lung cancer): 4 people, 16.00%
- High Blood Pressure: 3 people, 12.00%
- Memory Loss: 2 people, 8.00%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 8.00%
- Bipolar Disorder (mood disorder): 2 people, 8.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 8.00%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Ativan and have Optic neuropathy?
- Check whether Optic neuropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Ativan:
- Ativan (78,506 reports)
Optic neuropathy treatments and more:
- Optic neuropathy (2,298 reports)
How severe was Optic neuropathy and when was it recovered:
Expand to all the drugs that have ingredients of lorazepam:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ativan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Optic neuropathy:
- Optic neuropathy (258 drugs)
Browse all the conditions that are associated with Optic neuropathy:
- Optic neuropathy (451 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on lorazepam (the active ingredients of Ativan) and Ativan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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