Atomoxetine and Depression - a phase IV clinical study of FDA data

Summary:

Depression is reported as a side effect among people who take Atomoxetine (atomoxetine), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Fluoxetine, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Depression when taking Atomoxetine. It is created by eHealthMe based on reports of 1,183 people who have side effects when taking Atomoxetine from the FDA, and is updated regularly.

What is Atomoxetine?

Atomoxetine has active ingredients of atomoxetine. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,363 Atomoxetine users. Check the latest studies of Atomoxetine.

What is Depression?

Depression is found to be associated with 3,169 drugs and 4,130 conditions by eHealthMe. Check the latest studies of Depression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

1,183 people reported to have side effects when taking Atomoxetine.
Among them, 65 people (5.49%) have Depression.

Among these 65 people:

How long have people been on Atomoxetine when they have Depression? *

What is the gender of people who have Depression when taking Atomoxetine? *

female: 51.67 %
male: 48.33 %

What is the age of people who have Depression when taking Atomoxetine? *

What are other drugs people take besides Atomoxetine? *

What are other side effects people have besides Depression? *

Stress And Anxiety: 19 people, 29.23%
Suicidal Ideation: 18 people, 27.69%
Irritability: 14 people, 21.54%
Crying: 12 people, 18.46%
Insomnia (sleeplessness): 9 people, 13.85%
Drug Ineffective: 7 people, 10.77%
Euphoric Mood (excessively happy but may become angry or irritable): 7 people, 10.77%
Depressed Mood: 7 people, 10.77%
Hypomania (a mild form of mania, marked by elation and hyperactivity): 7 people, 10.77%
Fatigue (feeling of tiredness): 6 people, 9.23%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 7 people, 10.77%
Cystic Fibrosis (disease of the secretary glands): 4 people, 6.15%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 4.62%
Asthma: 3 people, 4.62%
Acne (skin problems that cause pimples): 2 people, 3.08%
Menopause (end of monthly cycles in women): 2 people, 3.08%
High Blood Cholesterol: 2 people, 3.08%
High Blood Pressure: 2 people, 3.08%
Stress And Anxiety: 2 people, 3.08%
Impulse-Control Disorder: 2 people, 3.08%

* Approximation only. Some reports may have incomplete information.

Do you take Atomoxetine and have Depression?

- Check whether Depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Atomoxetine:

Atomoxetine (1,363 reports)

Depression treatments and more:

Depression (652,162 reports)

Browse all side effects of Atomoxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression:

Depression (3,169 drugs)

Browse all the conditions that are associated with Depression:

Depression (4,130 conditions)

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on atomoxetine (the active ingredients of Atomoxetine) and Atomoxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.