Atripla and Intervertebral disc operation - a phase IV clinical study of FDA data

Summary:

Intervertebral disc operation is reported as a side effect among people who take Atripla (efavirenz; emtricitabine; tenofovir disoproxil fumarate), especially for people who are male, 40-49 old, have been taking the drug for 2 - 5 years also take Truvada, and have Hepatitis b.

The phase IV clinical study analyzes which people have Intervertebral disc operation when taking Atripla. It is created by eHealthMe based on reports of 35,479 people who have side effects when taking Atripla from the FDA, and is updated regularly.

What is Atripla?

Atripla has active ingredients of efavirenz; emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 36,036 Atripla users. Check the latest studies of Atripla.

What is Intervertebral disc operation?

Intervertebral disc operation is found to be associated with 271 drugs and 274 conditions by eHealthMe. Check the latest studies of Intervertebral disc operation.

On Jul, 19, 2026

35,479 people reported to have side effects when taking Atripla.
Among them, 11 people (0.03%) have Intervertebral disc operation.

Could Atripla cause Intervertebral disc operation?

Among these 11 people:

How long have people been on Atripla when they have Intervertebral disc operation? *

What is the gender of people who have Intervertebral disc operation when taking Atripla? *

female: 0.0 %
male: 100 %

What is the age of people who have Intervertebral disc operation when taking Atripla? *

What are other drugs people take besides Atripla? *

What are other side effects people have besides Intervertebral disc operation? *

Emotional Distress: 9 people, 81.82%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 9 people, 81.82%
Stress And Anxiety: 9 people, 81.82%
Bone Density Decreased: 9 people, 81.82%
Pain: 9 people, 81.82%
Osteopenia (a condition where bone mineral density is lower than normal): 7 people, 63.64%
Intervertebral Disc Degeneration (spinal disc degeneration): 5 people, 45.45%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 5 people, 45.45%
Spinal Stenosis (narrowing of spinal column): 5 people, 45.45%
Bone Loss: 5 people, 45.45%

What are the existing conditions these people have? *

Hepatitis B: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Atripla and have Intervertebral disc operation?

- Check whether Intervertebral disc operation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Atripla:

Atripla (36,036 reports)

Intervertebral disc operation treatments and more:

Intervertebral disc operation (1,662 reports)

How severe was Intervertebral disc operation and when was it recovered:

Intervertebral disc operation in Atripla

Expand to all the drugs that have ingredients of efavirenz; emtricitabine; tenofovir disoproxil fumarate:

Intervertebral disc operation and drugs with ingredients of efavirenz; emtricitabine; tenofovir disoproxil fumarate (11 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Atripla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc operation:

Intervertebral disc operation (271 drugs)

Browse all the conditions that are associated with Intervertebral disc operation:

Intervertebral disc operation (274 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on efavirenz; emtricitabine; tenofovir disoproxil fumarate (the active ingredients of Atripla) and Atripla (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.