Aubagio and Osteopenia - a phase IV clinical study of FDA data

Summary:

Osteopenia is reported as a side effect among people who take Aubagio (teriflunomide), especially for people who are female, 60+ old, also take Zyrtec, and have Cataplexy.

The phase IV clinical study analyzes which people have Osteopenia when taking Aubagio. It is created by eHealthMe based on reports of 49,894 people who have side effects when taking Aubagio from the FDA, and is updated regularly.

What is Aubagio?

Aubagio has active ingredients of teriflunomide. It is often used in multiple sclerosis. eHealthMe is studying from 50,041 Aubagio users. Check the latest studies of Aubagio.

What is Osteopenia?

Osteopenia (a condition where bone mineral density is lower than normal) is found to be associated with 1,437 drugs and 1,172 conditions by eHealthMe. Check the latest studies of Osteopenia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

49,894 people reported to have side effects when taking Aubagio.
Among them, 12 people (0.02%) have Osteopenia.

Among these 12 people:

What is the gender of people who have Osteopenia when taking Aubagio? *

female: 100 %
male: 0.0 %

What is the age of people who have Osteopenia when taking Aubagio? *

What are other drugs people take besides Aubagio? *

Zyrtec: 6 people, 50.00%
Ampyra: 5 people, 41.67%
Singulair: 5 people, 41.67%
Hydrocodone Bitartrate And Acetaminophen: 5 people, 41.67%
Lidoderm: 4 people, 33.33%
Oxycontin: 4 people, 33.33%
Xyrem: 4 people, 33.33%
Minocycline: 4 people, 33.33%
Lortab: 4 people, 33.33%
Linzess: 4 people, 33.33%

What are other side effects people have besides Osteopenia? *

Migraine (headache): 5 people, 41.67%
Pain: 4 people, 33.33%
Therapeutic Response Decreased (less preventive response): 4 people, 33.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 33.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 33.33%
Nerve Injury: 4 people, 33.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 33.33%
Diarrhea: 4 people, 33.33%
Osteomyelitis (infection of bone): 4 people, 33.33%
Hair Loss: 3 people, 25.00%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 33.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 33.33%
Pain: 1 person, 8.33%
Nausea (feeling of having an urge to vomit): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Aubagio and have Osteopenia?

- Check whether Osteopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aubagio:

Aubagio (50,041 reports)

Osteopenia treatments and more:

Osteopenia (46,948 reports)

Browse all side effects of Aubagio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteopenia:

Osteopenia (1,437 drugs)

Browse all the conditions that are associated with Osteopenia:

Osteopenia (1,172 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on teriflunomide (the active ingredients of Aubagio) and Aubagio (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.