Augmentin and Haemorrhoidal haemorrhage - a phase IV clinical study of FDA data

Summary:

Haemorrhoidal haemorrhage is reported as a side effect among people who take Augmentin (amoxicillin; clavulanate potassium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Paroxysmal nocturnal haemoglobinuria.

The phase IV clinical study analyzes which people have Haemorrhoidal haemorrhage when taking Augmentin. It is created by eHealthMe based on reports of 41,293 people who have side effects when taking Augmentin from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Haemorrhoidal haemorrhage?

Haemorrhoidal haemorrhage (bleeding from the haemorrhoids) is found to be associated with 625 drugs and 586 conditions by eHealthMe. Check the latest studies of Haemorrhoidal haemorrhage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

41,293 people reported to have side effects when taking Augmentin.
Among them, 19 people (0.05%) have Haemorrhoidal haemorrhage.

Could Augmentin cause Haemorrhoidal haemorrhage?

Among these 19 people:

How long have people been on Augmentin when they have Haemorrhoidal haemorrhage? *

What is the gender of people who have Haemorrhoidal haemorrhage when taking Augmentin? *

female: 57.89 %
male: 42.11 %

What is the age of people who have Haemorrhoidal haemorrhage when taking Augmentin? *

What are other drugs people take besides Augmentin? *

What are other side effects people have besides Haemorrhoidal haemorrhage? *

Diarrhea: 8 people, 42.11%
Anaemia (lack of blood): 7 people, 36.84%
Pneumonia: 7 people, 36.84%
Fever: 6 people, 31.58%
Joint Pain: 6 people, 31.58%
Dizziness: 6 people, 31.58%
Haematuria (presence of blood in urine): 5 people, 26.32%
Haemorrhage (bleeding): 5 people, 26.32%
Fatigue (feeling of tiredness): 5 people, 26.32%
Pain: 5 people, 26.32%

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 4 people, 21.05%
High Blood Pressure: 3 people, 15.79%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 15.79%
Anaemia (lack of blood): 3 people, 15.79%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 2 people, 10.53%
Multiple Myeloma (cancer of the plasma cells): 2 people, 10.53%
Osteomyelitis (infection of bone): 2 people, 10.53%
Menopause (end of monthly cycles in women): 2 people, 10.53%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 10.53%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and have Haemorrhoidal haemorrhage?

- Check whether Haemorrhoidal haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Augmentin:

Augmentin (42,620 reports)

Haemorrhoidal haemorrhage treatments and more:

Haemorrhoidal haemorrhage (6,194 reports)

How severe was Haemorrhoidal haemorrhage and when was it recovered:

Haemorrhoidal haemorrhage in Augmentin

Expand to all the drugs that have ingredients of amoxicillin; clavulanate potassium:

Haemorrhoidal haemorrhage and drugs with ingredients of amoxicillin; clavulanate potassium (23 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemorrhoidal haemorrhage:

Haemorrhoidal haemorrhage (625 drugs)

Browse all the conditions that are associated with Haemorrhoidal haemorrhage:

Haemorrhoidal haemorrhage (586 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium (the active ingredients of Augmentin) and Augmentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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