Augmentin and Hyperacusis - a phase IV clinical study of FDA data

Summary:

Hyperacusis is reported as a side effect among people who take Augmentin (amoxicillin; clavulanate potassium), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Oxycontin, and have Pain.

The phase IV clinical study analyzes which people have Hyperacusis when taking Augmentin. It is created by eHealthMe based on reports of 41,293 people who have side effects when taking Augmentin from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,618 Augmentin users. Check the latest studies of Augmentin.

What is Hyperacusis?

Hyperacusis (disorder in loudness perception) is found to be associated with 475 drugs and 600 conditions by eHealthMe. Check the latest studies of Hyperacusis.

On Oct, 02, 2025

41,293 people reported to have side effects when taking Augmentin.
Among them, 38 people (0.09%) have Hyperacusis.

Among these 38 people:

How long have people been on Augmentin when they have Hyperacusis? *

What is the gender of people who have Hyperacusis when taking Augmentin? *

female: 97.3 %
male: 2.7 %

What is the age of people who have Hyperacusis when taking Augmentin? *

What are other drugs people take besides Augmentin? *

What are other side effects people have besides Hyperacusis? *

Fatigue (feeling of tiredness): 32 people, 84.21%
Tinnitus (a ringing in the ears): 32 people, 84.21%
Joint Pain: 31 people, 81.58%
Rashes (redness): 31 people, 81.58%
Migraine (headache): 31 people, 81.58%
Photophobia (extreme sensitivity to light): 30 people, 78.95%
Dry Eyes (lack of adequate tears): 29 people, 76.32%
Nausea (feeling of having an urge to vomit): 29 people, 76.32%
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin): 29 people, 76.32%
Psychomotor Skills Impaired: 29 people, 76.32%

What are the existing conditions these people have? *

Pain: 30 people, 78.95%
Bladder Pain: 27 people, 71.05%
Hypersensitivity: 9 people, 23.68%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 7.89%
Psychotic Disorder: 3 people, 7.89%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 7.89%
Depression: 3 people, 7.89%
Thyroid Diseases: 2 people, 5.26%
Sleep Disorder: 2 people, 5.26%
Tinnitus (a ringing in the ears): 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and have Hyperacusis?

- Check whether Hyperacusis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Augmentin:

Augmentin (42,618 reports)

Hyperacusis treatments and more:

Hyperacusis (4,388 reports)

How severe was Hyperacusis and when was it recovered:

Hyperacusis in Augmentin

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperacusis:

Hyperacusis (475 drugs)

Browse all the conditions that are associated with Hyperacusis:

Hyperacusis (600 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium (the active ingredients of Augmentin) and Augmentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.