Augmentin and Hypercalcaemia of malignancy - a phase IV clinical study of FDA data

Summary:

Hypercalcaemia of malignancy is reported as a side effect among people who take Augmentin (amoxicillin; clavulanate potassium), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Bactrim, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Hypercalcaemia of malignancy when taking Augmentin. It is created by eHealthMe based on reports of 41,293 people who have side effects when taking Augmentin from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Hypercalcaemia of malignancy?

Hypercalcaemia of malignancy (elevated calcium (ca+) level in the blood with cancer) is found to be associated with 86 drugs and 112 conditions by eHealthMe. Check the latest studies of Hypercalcaemia of malignancy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

41,293 people reported to have side effects when taking Augmentin.
Among them, 11 people (0.03%) have Hypercalcaemia of malignancy.

Could Augmentin cause Hypercalcaemia of malignancy?

Among these 11 people:

How long have people been on Augmentin when they have Hypercalcaemia of malignancy? *

What is the gender of people who have Hypercalcaemia of malignancy when taking Augmentin? *

female: 9.09 %
male: 90.91 %

What is the age of people who have Hypercalcaemia of malignancy when taking Augmentin? *

What are other drugs people take besides Augmentin? *

What are other side effects people have besides Hypercalcaemia of malignancy? *

Fever: 11 people, 100.00%
Death: 9 people, 81.82%
Weight Decreased: 7 people, 63.64%
Weakness: 7 people, 63.64%
Nausea (feeling of having an urge to vomit): 7 people, 63.64%
Indigestion: 6 people, 54.55%
Fatigue (feeling of tiredness): 6 people, 54.55%
Pain: 6 people, 54.55%
Hyperhidrosis (abnormally increased sweating): 6 people, 54.55%
Dyspnea (difficult or laboured breathing): 6 people, 54.55%

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 54.55%
Richter's Syndrome (hairy cell cancer changes in fast growing b cell cancer tumour): 5 people, 45.45%
Pain: 5 people, 45.45%
Neoplasm Malignant (cancer tumour): 5 people, 45.45%
Multiple Myeloma (cancer of the plasma cells): 5 people, 45.45%
Metastases To Bone (cancer spreads to bone): 5 people, 45.45%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and have Hypercalcaemia of malignancy?

- Check whether Hypercalcaemia of malignancy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Augmentin:

Augmentin (42,620 reports)

Hypercalcaemia of malignancy treatments and more:

Hypercalcaemia of malignancy (1,132 reports)

How severe was Hypercalcaemia of malignancy and when was it recovered:

Hypercalcaemia of malignancy in Augmentin

Expand to all the drugs that have ingredients of amoxicillin; clavulanate potassium:

Hypercalcaemia of malignancy and drugs with ingredients of amoxicillin; clavulanate potassium

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercalcaemia of malignancy:

Hypercalcaemia of malignancy (86 drugs)

Browse all the conditions that are associated with Hypercalcaemia of malignancy:

Hypercalcaemia of malignancy (112 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium (the active ingredients of Augmentin) and Augmentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.