Augmentin and Obsessive-compulsive disorder - a phase IV clinical study of FDA data

Summary:

Obsessive-compulsive disorder is reported as a side effect among people who take Augmentin (amoxicillin; clavulanate potassium), especially for people who are female, 40-49 old, also take Wellbutrin, and have Depression.

The phase IV clinical study analyzes which people have Obsessive-compulsive disorder when taking Augmentin. It is created by eHealthMe based on reports of 41,293 people who have side effects when taking Augmentin from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Obsessive-compulsive disorder?

Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;) is found to be associated with 681 drugs and 1,308 conditions by eHealthMe. Check the latest studies of Obsessive-compulsive disorder.



On Jul, 02, 2026

41,293 people reported to have side effects when taking Augmentin.
Among them, 19 people (0.05%) have Obsessive-compulsive disorder.

Could Augmentin cause Obsessive-compulsive disorder?

Among these 19 people:

What is the gender of people who have Obsessive-compulsive disorder when taking Augmentin? *

  • female: 68.42 %
  • male: 31.58 %

What is the age of people who have Obsessive-compulsive disorder when taking Augmentin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 16.67 %
  • 20-29: 16.67 %
  • 30-39: 16.67 %
  • 40-49: 50.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Augmentin? *

  1. Wellbutrin: 7 people, 36.84%
  2. Abilify: 5 people, 26.32%
  3. Xanax: 5 people, 26.32%
  4. Lexapro: 5 people, 26.32%
  5. Levaquin: 5 people, 26.32%
  6. Tylenol: 4 people, 21.05%
  7. Nasacort: 4 people, 21.05%
  8. Mirapex: 4 people, 21.05%
  9. Zofran: 4 people, 21.05%
  10. Ondansetron: 4 people, 21.05%

What are other side effects people have besides Obsessive-compulsive disorder? *

  1. Headache (pain in head): 7 people, 36.84%
  2. Depression: 6 people, 31.58%
  3. Itching: 5 people, 26.32%
  4. Stress And Anxiety: 5 people, 26.32%
  5. Insomnia (sleeplessness): 4 people, 21.05%
  6. High Blood Pressure: 4 people, 21.05%
  7. Suicidal Ideation: 4 people, 21.05%
  8. Fatigue (feeling of tiredness): 4 people, 21.05%
  9. Pain: 4 people, 21.05%
  10. Decreased Interest: 3 people, 15.79%

What are the existing conditions these people have? *

  1. Depression: 7 people, 36.84%
  2. Bipolar Disorder (mood disorder): 5 people, 26.32%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 21.05%
  4. Uterine Contractions During Pregnancy: 3 people, 15.79%
  5. Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 15.79%
  6. Pain: 3 people, 15.79%
  7. Back Pain: 2 people, 10.53%
  8. Stress And Anxiety: 2 people, 10.53%
  9. Hypersensitivity: 2 people, 10.53%
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and have Obsessive-compulsive disorder?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Augmentin:

Obsessive-compulsive disorder treatments and more:

How severe was Obsessive-compulsive disorder and when was it recovered:

Expand to all the drugs that have ingredients of amoxicillin; clavulanate potassium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Obsessive-compulsive disorder:

Browse all the conditions that are associated with Obsessive-compulsive disorder:


How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium (the active ingredients of Augmentin) and Augmentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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