Augmentin and Scleroderma - a phase IV clinical study of FDA data

Summary:

Scleroderma is reported as a side effect among people who take Augmentin (amoxicillin; clavulanate potassium), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Nexium, and have Osteoporosis.

The phase IV clinical study analyzes which people have Scleroderma when taking Augmentin. It is created by eHealthMe based on reports of 41,293 people who have side effects when taking Augmentin from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Scleroderma?

Scleroderma (hard skin) is found to be associated with 940 drugs and 856 conditions by eHealthMe. Check the latest studies of Scleroderma.

On May, 06, 2026

41,293 people reported to have side effects when taking Augmentin.
Among them, 45 people (0.11%) have Scleroderma.

Among these 45 people:

How long have people been on Augmentin when they have Scleroderma? *

What is the gender of people who have Scleroderma when taking Augmentin? *

female: 82.22 %
male: 17.78 %

What is the age of people who have Scleroderma when taking Augmentin? *

What are other drugs people take besides Augmentin? *

What are other side effects people have besides Scleroderma? *

Pleural Effusion (water on the lungs): 30 people, 66.67%
Oedema Peripheral (superficial swelling): 29 people, 64.44%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 29 people, 64.44%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 29 people, 64.44%
Bone Pain: 29 people, 64.44%
Pain: 29 people, 64.44%
Pneumonia: 29 people, 64.44%
Bone Erosion: 28 people, 62.22%
Metastatic Neoplasm (spreadable cancer tumour): 28 people, 62.22%
Spinal Osteoarthritis (joint cartilage loss in spine): 28 people, 62.22%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 28 people, 62.22%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 27 people, 60.00%
Thrombocytopenia (decrease of platelets in blood): 11 people, 24.44%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 11.11%
Immunodeficiency Common Variable: 5 people, 11.11%
B-Lymphocyte Abnormalities (abnormal population of b lymphocytes in the blood, bone marrow, or tissues): 5 people, 11.11%
Hodgkin's Lymphoma (cancer originating from white blood cells): 3 people, 6.67%
Nausea (feeling of having an urge to vomit): 2 people, 4.44%
Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 2 people, 4.44%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 1 person, 2.22%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and have Scleroderma?

- Check whether Scleroderma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Augmentin:

Augmentin (42,620 reports)

Scleroderma treatments and more:

Scleroderma (10,958 reports)

How severe was Scleroderma and when was it recovered:

Scleroderma in Augmentin

Expand to all the drugs that have ingredients of amoxicillin; clavulanate potassium:

Scleroderma and drugs with ingredients of amoxicillin; clavulanate potassium (39 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Scleroderma:

Scleroderma (940 drugs)

Browse all the conditions that are associated with Scleroderma:

Scleroderma (856 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium (the active ingredients of Augmentin) and Augmentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.