Augmentin and Thin bones - a phase IV clinical study of FDA data

Summary:

Thin bones is reported as a side effect among people who take Augmentin (amoxicillin; clavulanate potassium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Aredia, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Thin bones when taking Augmentin. It is created by eHealthMe based on reports of 41,293 people who have side effects when taking Augmentin from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Thin bones?

Thin bones is found to be associated with 2,556 drugs and 1,908 conditions by eHealthMe. Check the latest studies of Thin bones.

On Oct, 27, 2025

41,293 people reported to have side effects when taking Augmentin.
Among them, 375 people (0.91%) have Thin bones.

Among these 375 people:

How long have people been on Augmentin when they have Thin bones? *

What is the gender of people who have Thin bones when taking Augmentin? *

female: 73.12 %
male: 26.88 %

What is the age of people who have Thin bones when taking Augmentin? *

What are other drugs people take besides Augmentin? *

What are other side effects people have besides Thin bones? *

Pain: 304 people, 81.07%
Stress And Anxiety: 252 people, 67.20%
Osteonecrosis Of Jaw (death of bone of jaw): 240 people, 64.00%
Osteopenia (a condition where bone mineral density is lower than normal): 196 people, 52.27%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 195 people, 52.00%
Anaemia (lack of blood): 185 people, 49.33%
Spinal Osteoarthritis (joint cartilage loss in spine): 171 people, 45.60%
Fatigue (feeling of tiredness): 157 people, 41.87%
Bone Disorder: 156 people, 41.60%
Back Pain: 153 people, 40.80%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 88 people, 23.47%
Hiv Infection: 43 people, 11.47%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 29 people, 7.73%
Pain: 28 people, 7.47%
Depression: 26 people, 6.93%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 23 people, 6.13%
Muscle Spasms (muscle contraction): 21 people, 5.60%
Osteopenia (a condition where bone mineral density is lower than normal): 19 people, 5.07%
Metastases To Bone (cancer spreads to bone): 19 people, 5.07%
Upper Respiratory Tract Infection: 17 people, 4.53%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and have Thin bones?

- Check whether Thin bones is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Augmentin:

Augmentin (42,620 reports)

Thin bones treatments and more:

Thin bones (290,718 reports)

How severe was Thin bones and when was it recovered:

Thin bones in Augmentin

Expand to all the drugs that have ingredients of amoxicillin; clavulanate potassium:

Thin bones and drugs with ingredients of amoxicillin; clavulanate potassium (524 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Augmentin side effects:

Augmentin side effect: Dyspnea (difficult or laboured breathing) (2,578 reports)
Augmentin side effect: Nausea (feeling of having an urge to vomit) (2,563 reports)

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Thin bones:

Browse all the drugs that are associated with Thin bones:

Thin bones (2,556 drugs)

Common conditions associated with Thin bones:

Browse all the conditions that are associated with Thin bones:

Thin bones (1,908 conditions)

Drugs similar to Augmentin and Thin bones :

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium (the active ingredients of Augmentin) and Augmentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.