Avalide and Ddd - a phase IV clinical study of FDA data

Summary:

Ddd is reported as a side effect among people who take Avalide (hydrochlorothiazide; irbesartan), especially for people who are male, 60+ old, also take Aredia, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Ddd when taking Avalide. It is created by eHealthMe based on reports of 5,642 people who have side effects when taking Avalide from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Ddd?

Ddd is found to be associated with 1,398 drugs and 1,391 conditions by eHealthMe. Check the latest studies of Ddd.

On Oct, 24, 2025

5,642 people reported to have side effects when taking Avalide.
Among them, 54 people (0.96%) have Ddd.

Among these 54 people:

* Approximation only. Some reports may have incomplete information.

Do you take Avalide and have Ddd?

- Check whether Ddd is associated with a drug or a condition (FREE)
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avalide:

Avalide (5,943 reports)

Ddd treatments and more:

Ddd (19,906 reports)

How severe was Ddd and when was it recovered:

Ddd in Avalide

Expand to all the drugs that have ingredients of hydrochlorothiazide; irbesartan:

Ddd and drugs with ingredients of hydrochlorothiazide; irbesartan (46 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Avalide side effects:

Browse all side effects of Avalide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Ddd:

Fosamax side effect: Ddd (3,043 reports)
Zometa side effect: Ddd (2,149 reports)
Prednisone side effect: Ddd (1,905 reports)
Aspirin side effect: Ddd (1,557 reports)
Humira side effect: Ddd (1,378 reports)
Aredia side effect: Ddd (1,331 reports)
Gabapentin side effect: Ddd (1,253 reports)
Methotrexate side effect: Ddd (1,183 reports)
Vioxx side effect: Ddd (1,076 reports)
Celebrex side effect: Ddd (1,050 reports)

Browse all the drugs that are associated with Ddd:

Ddd (1,398 drugs)

Common conditions associated with Ddd:

Browse all the conditions that are associated with Ddd:

Ddd (1,391 conditions)

Drugs similar to Avalide and Ddd :

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; irbesartan (the active ingredients of Avalide) and Avalide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.