Avalide and Duodenal ulcer aggravated - a phase IV clinical study of FDA data

Summary:

Duodenal ulcer aggravated is reported as a side effect among people who take Avalide (hydrochlorothiazide; irbesartan), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Vioxx, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Duodenal ulcer aggravated when taking Avalide. It is created by eHealthMe based on reports of 5,642 people who have side effects when taking Avalide from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Duodenal ulcer aggravated?

Duodenal ulcer aggravated is found to be associated with 1,477 drugs and 523 conditions by eHealthMe. Check the latest studies of Duodenal ulcer aggravated.

On Jul, 07, 2026

5,642 people reported to have side effects when taking Avalide.
Among them, 69 people (1.22%) have Duodenal ulcer aggravated.

Could Avalide cause Duodenal ulcer aggravated?

Among these 69 people:

How long have people been on Avalide when they have Duodenal ulcer aggravated? *

What is the gender of people who have Duodenal ulcer aggravated when taking Avalide? *

female: 60.94 %
male: 39.06 %

What is the age of people who have Duodenal ulcer aggravated when taking Avalide? *

What are other drugs people take besides Avalide? *

What are other side effects people have besides Duodenal ulcer aggravated? *

Anaemia (lack of blood): 30 people, 43.48%
Pain: 29 people, 42.03%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 26 people, 37.68%
Deformity (disfigurement): 25 people, 36.23%
Depression: 25 people, 36.23%
Neuropathy Peripheral (surface nerve damage): 24 people, 34.78%
Stress And Anxiety: 24 people, 34.78%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 23 people, 33.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 23 people, 33.33%
Impaired Healing: 22 people, 31.88%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 23 people, 33.33%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 12 people, 17.39%
Urinary Tract Infection: 9 people, 13.04%
Diabetes: 5 people, 7.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 7.25%
Pain: 5 people, 7.25%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 4.35%
Breast Cancer Metastatic: 3 people, 4.35%
Cardiac Disorder: 3 people, 4.35%
Depression: 3 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Avalide and have Duodenal ulcer aggravated?

- Check whether Duodenal ulcer aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avalide:

Avalide (5,943 reports)

Duodenal ulcer aggravated treatments and more:

Duodenal ulcer aggravated (25 reports)

How severe was Duodenal ulcer aggravated and when was it recovered:

Duodenal ulcer aggravated in Avalide

Expand to all the drugs that have ingredients of hydrochlorothiazide; irbesartan:

Duodenal ulcer aggravated and drugs with ingredients of hydrochlorothiazide; irbesartan

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avalide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Duodenal ulcer aggravated:

Duodenal ulcer aggravated (1,477 drugs)

Browse all the conditions that are associated with Duodenal ulcer aggravated:

Duodenal ulcer aggravated (523 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; irbesartan (the active ingredients of Avalide) and Avalide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.