Avalide and Wheezing - a phase IV clinical study of FDA data

Summary:

Wheezing is reported as a side effect among people who take Avalide (hydrochlorothiazide; irbesartan), especially for people who are female, 60+ old, also take Vioxx, and have Pain.

The phase IV clinical study analyzes which people have Wheezing when taking Avalide. It is created by eHealthMe based on reports of 5,642 people who have side effects when taking Avalide from the FDA, and is updated regularly.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.

What is Wheezing?

Wheezing (a high-pitched whistling sound made while you breath) is found to be associated with 1,836 drugs and 2,206 conditions by eHealthMe. Check the latest studies of Wheezing.

On Apr, 12, 2026

5,642 people reported to have side effects when taking Avalide.
Among them, 30 people (0.53%) have Wheezing.

Among these 30 people:

What is the gender of people who have Wheezing when taking Avalide? *

female: 76.67 %
male: 23.33 %

What is the age of people who have Wheezing when taking Avalide? *

What are other drugs people take besides Avalide? *

What are other side effects people have besides Wheezing? *

Cough: 15 people, 50.00%
Dyspnea (difficult or laboured breathing): 11 people, 36.67%
Dizziness: 10 people, 33.33%
Abdominal Pain: 9 people, 30.00%
Anaemia (lack of blood): 8 people, 26.67%
Fatigue (feeling of tiredness): 8 people, 26.67%
Fever: 7 people, 23.33%
Depression: 7 people, 23.33%
Stable Angina (a constant chest pain): 6 people, 20.00%
Nausea (feeling of having an urge to vomit): 6 people, 20.00%

What are the existing conditions these people have? *

Sinusitis (inflammation of sinus): 5 people, 16.67%
Pain: 5 people, 16.67%
Back Pain: 4 people, 13.33%
Depression: 4 people, 13.33%
Sleep Disorder: 4 people, 13.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 10.00%
Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 10.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 10.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 10.00%
Fatigue (feeling of tiredness): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Avalide and have Wheezing?

- Check whether Wheezing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avalide:

Avalide (5,943 reports)

Wheezing treatments and more:

Wheezing (77,220 reports)

How severe was Wheezing and when was it recovered:

Wheezing in Avalide

Expand to all the drugs that have ingredients of hydrochlorothiazide; irbesartan:

Wheezing and drugs with ingredients of hydrochlorothiazide; irbesartan

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avalide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Wheezing:

Wheezing (1,836 drugs)

Browse all the conditions that are associated with Wheezing:

Wheezing (2,206 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; irbesartan (the active ingredients of Avalide) and Avalide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.