Avandamet and Anorexia - a phase IV clinical study of FDA data

Summary:

Anorexia is reported as a side effect among people who take Avandamet (metformin hydrochloride; rosiglitazone maleate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Byetta, and have High blood pressure.

The phase IV clinical study analyzes which people have Anorexia when taking Avandamet. It is created by eHealthMe based on reports of 16,018 people who have side effects when taking Avandamet from the FDA, and is updated regularly.

What is Avandamet?

Avandamet has active ingredients of metformin hydrochloride; rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 16,084 Avandamet users. Check the latest studies of Avandamet.

What is Anorexia?

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight) is found to be associated with 1,121 drugs and 1,686 conditions by eHealthMe. Check the latest studies of Anorexia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

16,018 people reported to have side effects when taking Avandamet.
Among them, 58 people (0.36%) have Anorexia.

Among these 58 people:

How long have people been on Avandamet when they have Anorexia? *

What is the gender of people who have Anorexia when taking Avandamet? *

female: 67.86 %
male: 32.14 %

What is the age of people who have Anorexia when taking Avandamet? *

What are other drugs people take besides Avandamet? *

What are other side effects people have besides Anorexia? *

Nausea (feeling of having an urge to vomit): 26 people, 44.83%
Weight Decreased: 20 people, 34.48%
Nausea And Vomiting: 16 people, 27.59%
Fatigue (feeling of tiredness): 13 people, 22.41%
Oedema Peripheral (superficial swelling): 13 people, 22.41%
Diarrhea: 11 people, 18.97%
Blood Glucose Increased: 8 people, 13.79%
Anaemia (lack of blood): 8 people, 13.79%
Abdominal Pain: 7 people, 12.07%
Joint Pain: 7 people, 12.07%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 5.17%
High Blood Pressure: 3 people, 5.17%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 3.45%
Respiratory Disorder (respiratory disease): 1 person, 1.72%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 1.72%
Hypertriglyceridaemia (excess of triglycerides in the blood): 1 person, 1.72%
Gout (uric acid crystals building up in the body): 1 person, 1.72%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 1 person, 1.72%
Gastric Ulcer (stomach ulcer): 1 person, 1.72%
Depression: 1 person, 1.72%

* Approximation only. Some reports may have incomplete information.

Do you take Avandamet and have Anorexia?

- Check whether Anorexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avandamet:

Avandamet (16,084 reports)

Anorexia treatments and more:

Anorexia (30,919 reports)

How severe was Anorexia and when was it recovered:

Anorexia in Avandamet

Expand to all the drugs that have ingredients of metformin hydrochloride; rosiglitazone maleate:

Anorexia and drugs with ingredients of metformin hydrochloride; rosiglitazone maleate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avandamet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anorexia:

Anorexia (1,121 drugs)

Browse all the conditions that are associated with Anorexia:

Anorexia (1,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride; rosiglitazone maleate (the active ingredients of Avandamet) and Avandamet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.