Avandaryl and Muscle spasms - a phase IV clinical study of FDA data

Summary:

Muscle spasms is reported as a side effect among people who take Avandaryl (glimepiride; rosiglitazone maleate), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Lipitor, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Muscle spasms when taking Avandaryl. It is created by eHealthMe based on reports of 2,654 people who have side effects when taking Avandaryl from the FDA, and is updated regularly.

What is Avandaryl?

Avandaryl has active ingredients of glimepiride; rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 2,660 Avandaryl users. Check the latest studies of Avandaryl.

What is Muscle spasms?

Muscle spasms (muscle contraction) is found to be associated with 2,670 drugs and 3,100 conditions by eHealthMe. Check the latest studies of Muscle spasms.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

2,654 people reported to have side effects when taking Avandaryl.
Among them, 14 people (0.53%) have Muscle spasms.

Among these 14 people:

How long have people been on Avandaryl when they have Muscle spasms? *

What is the gender of people who have Muscle spasms when taking Avandaryl? *

female: 64.29 %
male: 35.71 %

What is the age of people who have Muscle spasms when taking Avandaryl? *

What are other drugs people take besides Avandaryl? *

What are other side effects people have besides Muscle spasms? *

Chest Pain: 4 people, 28.57%
Weakness: 3 people, 21.43%
Diarrhea: 3 people, 21.43%
Pain In Extremity: 3 people, 21.43%
Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 14.29%
Dyspnea (difficult or laboured breathing): 2 people, 14.29%
Blood Glucose Decreased: 2 people, 14.29%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.14%
Constipation: 1 person, 7.14%
Fall: 1 person, 7.14%

What are the existing conditions these people have? *

Type 2 Diabetes: 2 people, 14.29%
High Blood Cholesterol: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Avandaryl and have Muscle spasms?

- Check whether Muscle spasms is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avandaryl:

Avandaryl (2,660 reports)

Muscle spasms treatments and more:

Muscle spasms (238,419 reports)

How severe was Muscle spasms and when was it recovered:

Muscle spasms in Avandaryl

Expand to all the drugs that have ingredients of glimepiride; rosiglitazone maleate:

Muscle spasms and drugs with ingredients of glimepiride; rosiglitazone maleate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avandaryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle spasms:

Muscle spasms (2,670 drugs)

Browse all the conditions that are associated with Muscle spasms:

Muscle spasms (3,100 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glimepiride; rosiglitazone maleate (the active ingredients of Avandaryl) and Avandaryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.