Avapro and Coma - a phase IV clinical study of FDA data

Summary:

Coma is reported as a side effect among people who take Avapro (irbesartan), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lipitor, and have Chronic renal failure.

The phase IV clinical study analyzes which people have Coma when taking Avapro. It is created by eHealthMe based on reports of 18,804 people who have side effects when taking Avapro from the FDA, and is updated regularly.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

What is Coma?

Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,852 drugs and 3,193 conditions by eHealthMe. Check the latest studies of Coma.

On Jan, 13, 2026

18,804 people reported to have side effects when taking Avapro.
Among them, 28 people (0.15%) have Coma.

Among these 28 people:

How long have people been on Avapro when they have Coma? *

What is the gender of people who have Coma when taking Avapro? *

female: 82.14 %
male: 17.86 %

What is the age of people who have Coma when taking Avapro? *

What are other drugs people take besides Avapro? *

What are other side effects people have besides Coma? *

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 10 people, 35.71%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 8 people, 28.57%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 21.43%
Weakness: 6 people, 21.43%
Hypoglycemia (low blood sugar): 5 people, 17.86%
Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 5 people, 17.86%
Weight Decreased: 5 people, 17.86%
Blood Glucose Increased: 5 people, 17.86%
Acute Kidney Failure: 5 people, 17.86%
Dehydration (dryness resulting from the removal of water): 5 people, 17.86%

What are the existing conditions these people have? *

Chronic Renal Failure (kidney failure): 6 people, 21.43%
Hyperkalemia (damage to or disease of the kidney): 5 people, 17.86%
Respiratory Tract Infection: 5 people, 17.86%
Bipolar Disorder (mood disorder): 4 people, 14.29%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 10.71%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 7.14%
Back Pain: 2 people, 7.14%
Depression: 2 people, 7.14%
Dizziness: 2 people, 7.14%
High Blood Cholesterol: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Avapro and have Coma?

- Check whether Coma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avapro:

Avapro (19,840 reports)

Coma treatments and more:

Coma (57,420 reports)

Browse all side effects of Avapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coma:

Coma (2,852 drugs)

Browse all the conditions that are associated with Coma:

Coma (3,193 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on irbesartan (the active ingredients of Avapro) and Avapro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.