Avapro and Mitral valve incompetence - a phase IV clinical study of FDA data

Summary:

Mitral valve incompetence is reported as a side effect among people who take Avapro (irbesartan), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Vioxx, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Mitral valve incompetence when taking Avapro. It is created by eHealthMe based on reports of 18,804 people who have side effects when taking Avapro from the FDA, and is updated regularly.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

What is Mitral valve incompetence?

Mitral valve incompetence (inefficient heart valve) is found to be associated with 1,435 drugs and 1,279 conditions by eHealthMe. Check the latest studies of Mitral valve incompetence.

On Aug, 08, 2026

18,804 people reported to have side effects when taking Avapro.
Among them, 95 people (0.51%) have Mitral valve incompetence.

Could Avapro cause Mitral valve incompetence?

Among these 95 people:

How long have people been on Avapro when they have Mitral valve incompetence? *

What is the gender of people who have Mitral valve incompetence when taking Avapro? *

female: 50 %
male: 50 %

What is the age of people who have Mitral valve incompetence when taking Avapro? *

What are other drugs people take besides Avapro? *

What are other side effects people have besides Mitral valve incompetence? *

Tricuspid Valve Incompetence (inefficient heart valve): 45 people, 47.37%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 41 people, 43.16%
Heart Attack: 35 people, 36.84%
Cardiac Failure Congestive: 35 people, 36.84%
High Blood Cholesterol: 32 people, 33.68%
Chest Pain: 31 people, 32.63%
Enlarged Heart: 29 people, 30.53%
Dyspnea (difficult or laboured breathing): 24 people, 25.26%
Back Pain: 23 people, 24.21%
Weakness: 22 people, 23.16%

What are the existing conditions these people have? *

High Blood Cholesterol: 7 people, 7.37%
Cardiac Failure Congestive: 6 people, 6.32%
Multiple Myeloma (cancer of the plasma cells): 5 people, 5.26%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 5.26%
Depression: 5 people, 5.26%
Prostate Cancer Metastatic: 4 people, 4.21%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 4.21%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 3.16%
Seasonal Allergy (allergic condition due to certain season): 3 people, 3.16%
Ill-Defined Disorder: 2 people, 2.11%

* Approximation only. Some reports may have incomplete information.

Do you take Avapro and have Mitral valve incompetence?

- Check whether Mitral valve incompetence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avapro:

Avapro (19,840 reports)

Browse all side effects of Avapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mitral valve incompetence:

Mitral valve incompetence (1,435 drugs)

Browse all the conditions that are associated with Mitral valve incompetence:

Mitral valve incompetence (1,279 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on irbesartan (the active ingredients of Avapro) and Avapro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.