Avastin and Injection site extravasation - a phase IV clinical study of FDA data

Summary:

Injection site extravasation is reported as a side effect among people who take Avastin (bevacizumab), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Xeloda, and have Colon cancer.

The phase IV clinical study analyzes which people have Injection site extravasation when taking Avastin. It is created by eHealthMe based on reports of 75,729 people who have side effects when taking Avastin from the FDA, and is updated regularly.

What is Avastin?

Avastin has active ingredients of bevacizumab. It is often used in high blood cholesterol. eHealthMe is studying from 76,365 Avastin users. Check the latest studies of Avastin.

What is Injection site extravasation?

Injection site extravasation (flow of (blood or lymph) from injection site) is found to be associated with 555 drugs and 729 conditions by eHealthMe. Check the latest studies of Injection site extravasation.



On Aug, 07, 2026

75,729 people reported to have side effects when taking Avastin.
Among them, 31 people (0.04%) have Injection site extravasation.

Could Avastin cause Injection site extravasation?

Among these 31 people:

How long have people been on Avastin when they have Injection site extravasation? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 25 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Injection site extravasation when taking Avastin? *

  • female: 48 %
  • male: 52 %

What is the age of people who have Injection site extravasation when taking Avastin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 11.11 %
  • 30-39: 5.56 %
  • 40-49: 22.22 %
  • 50-59: 22.22 %
  • 60+: 38.89 %

What are other drugs people take besides Avastin? *

  1. Xeloda: 4 people, 12.90%
  2. Fluorouracil: 3 people, 9.68%
  3. Oxaliplatin: 3 people, 9.68%
  4. Dexamethasone: 3 people, 9.68%
  5. Taxol: 2 people, 6.45%
  6. Estrogel: 2 people, 6.45%
  7. Emend: 2 people, 6.45%
  8. Ondansetron: 2 people, 6.45%
  9. Solu-Medrol: 2 people, 6.45%
  10. Aloxi: 2 people, 6.45%

What are other side effects people have besides Injection site extravasation? *

  1. Fatigue (feeling of tiredness): 6 people, 19.35%
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 4 people, 12.90%
  3. Lymphocyte Count Decreased: 3 people, 9.68%
  4. Protein Urine: 3 people, 9.68%
  5. Injection Site Pain: 3 people, 9.68%
  6. Infusion Related Reaction: 3 people, 9.68%
  7. Muscle Spasms (muscle contraction): 3 people, 9.68%
  8. Red Cell Distribution Width Increased: 3 people, 9.68%
  9. Eosinophil Count Increased: 2 people, 6.45%
  10. Oedema (fluid collection in tissue): 2 people, 6.45%

What are the existing conditions these people have? *

  1. Colon Cancer Metastatic (cancer of colon spreads to other part of body): 4 people, 12.90%
  2. Colon Cancer: 4 people, 12.90%
  3. Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 9.68%
  4. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 3 people, 9.68%
  5. Ovarian Cancer Metastatic (cancer of ovary spreads to other organ or parts): 2 people, 6.45%
  6. Renal Cell Carcinoma (a kidney cancer): 1 person, 3.23%
  7. Prostate Cancer: 1 person, 3.23%
  8. Neuroendocrine Tumor: 1 person, 3.23%
  9. Neoplasm Malignant (cancer tumour): 1 person, 3.23%
  10. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Avastin and have Injection site extravasation?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avastin:

Injection site extravasation treatments and more:

How severe was Injection site extravasation and when was it recovered:

Expand to all the drugs that have ingredients of bevacizumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avastin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site extravasation:

Browse all the conditions that are associated with Injection site extravasation:


How the study uses the data?

The study uses data from the FDA. It is based on bevacizumab (the active ingredients of Avastin) and Avastin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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