Avastin and Proctalgia - a phase IV clinical study of FDA data

Summary:

Proctalgia is reported as a side effect among people who take Avastin (bevacizumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Xeloda, and have Colon cancer.

The phase IV clinical study analyzes which people have Proctalgia when taking Avastin. It is created by eHealthMe based on reports of 75,729 people who have side effects when taking Avastin from the FDA, and is updated regularly.

What is Avastin?

Avastin has active ingredients of bevacizumab. It is often used in high blood cholesterol. eHealthMe is studying from 76,365 Avastin users. Check the latest studies of Avastin.

What is Proctalgia?

Proctalgia (pain in the rectum) is found to be associated with 769 drugs and 774 conditions by eHealthMe. Check the latest studies of Proctalgia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

75,729 people reported to have side effects when taking Avastin.
Among them, 98 people (0.13%) have Proctalgia.

Among these 98 people:

How long have people been on Avastin when they have Proctalgia? *

What is the gender of people who have Proctalgia when taking Avastin? *

female: 55.32 %
male: 44.68 %

What is the age of people who have Proctalgia when taking Avastin? *

What are other drugs people take besides Avastin? *

What are other side effects people have besides Proctalgia? *

Diarrhea: 35 people, 35.71%
Constipation: 28 people, 28.57%
Fatigue (feeling of tiredness): 27 people, 27.55%
Weakness: 23 people, 23.47%
Nausea (feeling of having an urge to vomit): 22 people, 22.45%
Disease Progression: 20 people, 20.41%
Death: 20 people, 20.41%
Fever: 14 people, 14.29%
Thrombocytopenia (decrease of platelets in blood): 14 people, 14.29%
Nausea And Vomiting: 13 people, 13.27%

What are the existing conditions these people have? *

Colon Cancer: 21 people, 21.43%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 20 people, 20.41%
Rectal Cancer (cancer of rectum): 11 people, 11.22%
Breast Cancer: 8 people, 8.16%
Ovarian Cancer (cancer of ovary): 7 people, 7.14%
Colon Cancer Metastatic (cancer of colon spreads to other part of body): 6 people, 6.12%
Pain: 4 people, 4.08%
Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 4.08%
Cervix Carcinoma (cancer of cervix): 3 people, 3.06%
Large Intestine Carcinoma (cancer of large intestine): 3 people, 3.06%

* Approximation only. Some reports may have incomplete information.

Do you take Avastin and have Proctalgia?

- Check whether Proctalgia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avastin:

Avastin (76,365 reports)

Proctalgia treatments and more:

Proctalgia (9,250 reports)

Browse all side effects of Avastin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Proctalgia:

Proctalgia (769 drugs)

Browse all the conditions that are associated with Proctalgia:

Proctalgia (774 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bevacizumab (the active ingredients of Avastin) and Avastin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.