Avastin and Skin hyperpigmentation - a phase IV clinical study of FDA data

Summary:

Skin hyperpigmentation is reported as a side effect among people who take Avastin (bevacizumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Alimta, and have Breast cancer.

The phase IV clinical study analyzes which people have Skin hyperpigmentation when taking Avastin. It is created by eHealthMe based on reports of 75,729 people who have side effects when taking Avastin from the FDA, and is updated regularly.

What is Avastin?

Avastin has active ingredients of bevacizumab. It is often used in high blood cholesterol. eHealthMe is studying from 76,365 Avastin users. Check the latest studies of Avastin.

What is Skin hyperpigmentation?

Skin hyperpigmentation (disorders affect the colour of your skin) is found to be associated with 649 drugs and 811 conditions by eHealthMe. Check the latest studies of Skin hyperpigmentation.

On Jul, 04, 2026

75,729 people reported to have side effects when taking Avastin.
Among them, 49 people (0.06%) have Skin hyperpigmentation.

Could Avastin cause Skin hyperpigmentation?

Among these 49 people:

How long have people been on Avastin when they have Skin hyperpigmentation? *

What is the gender of people who have Skin hyperpigmentation when taking Avastin? *

female: 72.34 %
male: 27.66 %

What is the age of people who have Skin hyperpigmentation when taking Avastin? *

What are other drugs people take besides Avastin? *

What are other side effects people have besides Skin hyperpigmentation? *

High Blood Pressure: 18 people, 36.73%
Rashes (redness): 16 people, 32.65%
Diarrhea: 16 people, 32.65%
Nosebleed (bleeding from nose): 11 people, 22.45%
Neuropathy Peripheral (surface nerve damage): 9 people, 18.37%
Nail Disorder (disease of nail): 9 people, 18.37%
Fever: 8 people, 16.33%
Nausea (feeling of having an urge to vomit): 8 people, 16.33%
Abdominal Pain: 8 people, 16.33%
Laryngitis (inflammation of the larynx): 7 people, 14.29%

What are the existing conditions these people have? *

Breast Cancer: 9 people, 18.37%
Lung Neoplasm Malignant (cancer tumour of lung): 7 people, 14.29%
Toothaches (tooth pain): 6 people, 12.24%
Fever: 6 people, 12.24%
Colon Cancer: 5 people, 10.20%
Lung Cancer - Non-Small Cell (lung cancer): 5 people, 10.20%
Breast Cancer Female: 4 people, 8.16%
Metastases To Liver (cancer spreads to liver): 2 people, 4.08%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 4.08%
Breast Cancer Metastatic: 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Avastin and have Skin hyperpigmentation?

- Check whether Skin hyperpigmentation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avastin:

Avastin (76,365 reports)

Browse all side effects of Avastin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin hyperpigmentation:

Skin hyperpigmentation (649 drugs)

Browse all the conditions that are associated with Skin hyperpigmentation:

Skin hyperpigmentation (811 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bevacizumab (the active ingredients of Avastin) and Avastin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.