Avonex and Umbilical hernia - a phase IV clinical study of FDA data

Summary:

Umbilical hernia is reported as a side effect among people who take Avonex (interferon beta 1a), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Xanax, and have Osteoporosis.

The phase IV clinical study analyzes which people have Umbilical hernia when taking Avonex. It is created by eHealthMe based on reports of 198,141 people who have side effects when taking Avonex from the FDA, and is updated regularly.

What is Avonex?

Avonex has active ingredients of interferon beta 1a. It is often used in multiple sclerosis. eHealthMe is studying from 198,544 Avonex users. Check the latest studies of Avonex.

What is Umbilical hernia?

Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button) is found to be associated with 644 drugs and 676 conditions by eHealthMe. Check the latest studies of Umbilical hernia.



On Aug, 12, 2026

198,141 people reported to have side effects when taking Avonex.
Among them, 54 people (0.03%) have Umbilical hernia.

Could Avonex cause Umbilical hernia?

Among these 54 people:

How long have people been on Avonex when they have Umbilical hernia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 16.67 %
  • 6 - 12 months: 33.33 %
  • 1 - 2 years: 16.67 %
  • 2 - 5 years: 16.67 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 0.0 %

What is the gender of people who have Umbilical hernia when taking Avonex? *

  • female: 86.79 %
  • male: 13.21 %

What is the age of people who have Umbilical hernia when taking Avonex? *

  • 0-1: 2.22 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 4.44 %
  • 30-39: 17.78 %
  • 40-49: 8.89 %
  • 50-59: 51.11 %
  • 60+: 15.56 %

What are other drugs people take besides Avonex? *

  1. Xanax: 6 people, 11.11%
  2. Ambien: 5 people, 9.26%
  3. Aspirin: 5 people, 9.26%
  4. Requip: 4 people, 7.41%
  5. Tysabri: 4 people, 7.41%
  6. Cymbalta: 4 people, 7.41%
  7. Zoloft: 3 people, 5.56%
  8. Effexor: 3 people, 5.56%
  9. Premarin: 3 people, 5.56%
  10. Prednisone: 2 people, 3.70%

What are other side effects people have besides Umbilical hernia? *

  1. Nausea (feeling of having an urge to vomit): 7 people, 12.96%
  2. Nausea And Vomiting: 7 people, 12.96%
  3. Gallstones (stone formation by bile component): 7 people, 12.96%
  4. Diabetes: 7 people, 12.96%
  5. Constipation: 7 people, 12.96%
  6. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 6 people, 11.11%
  7. Influenza Like Illness: 6 people, 11.11%
  8. Chest Pain: 5 people, 9.26%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.26%
  10. Fatigue (feeling of tiredness): 5 people, 9.26%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 2 people, 3.70%
  2. Stress And Anxiety: 1 person, 1.85%
  3. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 1.85%
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 1.85%
  5. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 1.85%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 1.85%
  7. Fall: 1 person, 1.85%
  8. Depression: 1 person, 1.85%
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 1.85%

* Approximation only. Some reports may have incomplete information.

Do you take Avonex and have Umbilical hernia?

- Check whether Umbilical hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avonex:

Umbilical hernia treatments and more:

How severe was Umbilical hernia and when was it recovered:

Expand to all the drugs that have ingredients of interferon beta 1a:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avonex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Umbilical hernia:

Browse all the conditions that are associated with Umbilical hernia:


How the study uses the data?

The study uses data from the FDA. It is based on interferon beta 1a (the active ingredients of Avonex) and Avonex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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