Avonex and Urine discoloration - a phase IV clinical study of FDA data

Summary:

Urine discoloration is reported as a side effect among people who take Avonex (interferon beta 1a), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Levothyroxine Sodium,.

The phase IV clinical study analyzes which people have Urine discoloration when taking Avonex. It is created by eHealthMe based on reports of 198,141 people who have side effects when taking Avonex from the FDA, and is updated regularly.

What is Avonex?

Avonex has active ingredients of interferon beta 1a. It is often used in multiple sclerosis. eHealthMe is studying from 198,544 Avonex users. Check the latest studies of Avonex.

What is Urine discoloration?

Urine discoloration is found to be associated with 222 drugs and 71 conditions by eHealthMe. Check the latest studies of Urine discoloration.



On Jul, 21, 2026

198,141 people reported to have side effects when taking Avonex.
Among them, 14 people (0.01%) have Urine discoloration.

Could Avonex cause Urine discoloration?

Among these 14 people:

How long have people been on Avonex when they have Urine discoloration? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 50 %
  • 10+ years: 0.0 %

What is the gender of people who have Urine discoloration when taking Avonex? *

  • female: 42.86 %
  • male: 57.14 %

What is the age of people who have Urine discoloration when taking Avonex? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 35.71 %
  • 40-49: 35.71 %
  • 50-59: 28.57 %
  • 60+: 0.0 %

What are other drugs people take besides Avonex? *

  1. Zoloft: 2 people, 14.29%
  2. Solu-Medrol: 2 people, 14.29%
  3. Provigil: 2 people, 14.29%
  4. Ogen: 2 people, 14.29%
  5. Neurontin: 2 people, 14.29%
  6. Levothyroxine Sodium: 2 people, 14.29%
  7. Prozac: 1 person, 7.14%
  8. Premarin: 1 person, 7.14%
  9. Novantrone: 1 person, 7.14%
  10. Menest: 1 person, 7.14%

What are other side effects people have besides Urine discoloration? *

  1. Liver Function Tests Nos Abnormal: 6 people, 42.86%
  2. Hepatitis Acute: 3 people, 21.43%
  3. Muscle Aches (muscle pain): 3 people, 21.43%
  4. Weight Decreased: 2 people, 14.29%
  5. Blood Bilirubin Increased: 2 people, 14.29%
  6. Hepatocellular Damage (liver damage): 2 people, 14.29%
  7. Influenza Like Illness: 2 people, 14.29%
  8. Flatulence (flatus expelled through the anus): 2 people, 14.29%
  9. Nausea (feeling of having an urge to vomit): 2 people, 14.29%
  10. Multiple Sclerosis Aggravated (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Avonex and have Urine discoloration?

- Check whether Urine discoloration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avonex:

Urine discoloration treatments and more:

How severe was Urine discoloration and when was it recovered:

Expand to all the drugs that have ingredients of interferon beta 1a:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Avonex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urine discoloration:

Browse all the conditions that are associated with Urine discoloration:


How the study uses the data?

The study uses data from the FDA. It is based on interferon beta 1a (the active ingredients of Avonex) and Avonex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: