Ayvakit and Muscle spasms - a phase IV clinical study of FDA data

Summary:

Muscle spasms is reported as a side effect among people who take Ayvakit (avapritinib), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Epipen, and have Systemic mastocytosis.

The phase IV clinical study analyzes which people have Muscle spasms when taking Ayvakit. It is created by eHealthMe based on reports of 7,362 people who have side effects when taking Ayvakit from the FDA, and is updated regularly.

What is Ayvakit?

Ayvakit has active ingredients of avapritinib. eHealthMe is studying from 7,362 Ayvakit users. Check the latest studies of Ayvakit.

What is Muscle spasms?

Muscle spasms (muscle contraction) is found to be associated with 2,676 drugs and 3,100 conditions by eHealthMe. Check the latest studies of Muscle spasms.

On Jul, 11, 2026

7,362 people reported to have side effects when taking Ayvakit.
Among them, 68 people (0.92%) have Muscle spasms.

Among these 68 people:

How long have people been on Ayvakit when they have Muscle spasms? *

What is the gender of people who have Muscle spasms when taking Ayvakit? *

female: 63.24 %
male: 36.76 %

What is the age of people who have Muscle spasms when taking Ayvakit? *

What are other drugs people take besides Ayvakit? *

What are other side effects people have besides Muscle spasms? *

Fatigue (feeling of tiredness): 27 people, 39.71%
Nausea (feeling of having an urge to vomit): 27 people, 39.71%
Diarrhea: 16 people, 23.53%
Pain: 14 people, 20.59%
Rashes (redness): 14 people, 20.59%
Pain In Extremity: 14 people, 20.59%
Peripheral Swelling: 14 people, 20.59%
Weakness: 13 people, 19.12%
Dyspnea (difficult or laboured breathing): 13 people, 19.12%
Anaemia (lack of blood): 11 people, 16.18%

What are the existing conditions these people have? *

Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 39 people, 57.35%
Gastrointestinal Stromal Tumor: 15 people, 22.06%
Haematopoietic Neoplasm (clonal disorders of blood cells cause abnormal mass of tissue cell): 5 people, 7.35%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 4.41%
Urticaria Pigmentosa (skin disease that produces patches of darker skin (lesions) and very bad itching): 2 people, 2.94%
Neoplasm Malignant (cancer tumour): 2 people, 2.94%
Mastocytic Leukaemia (presence of large numbers of tissue mast cells in the peripheral blood without skin lesions): 2 people, 2.94%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 1 person, 1.47%
Pain: 1 person, 1.47%
Nausea And Vomiting: 1 person, 1.47%

* Approximation only. Some reports may have incomplete information.

Do you take Ayvakit and have Muscle spasms?

- Check whether Muscle spasms is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ayvakit:

Ayvakit (7,362 reports)

Muscle spasms treatments and more:

Muscle spasms (238,418 reports)

Browse all side effects of Ayvakit:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle spasms:

Muscle spasms (2,676 drugs)

Browse all the conditions that are associated with Muscle spasms:

Muscle spasms (3,100 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on avapritinib (the active ingredients of Ayvakit) and Ayvakit (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.