Azactam and Cholestasis - a phase IV clinical study of FDA data

Summary:

Cholestasis is reported as a side effect among people who take Azactam (aztreonam), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Omeprazole, and have Device related infection.

The phase IV clinical study analyzes which people have Cholestasis when taking Azactam. It is created by eHealthMe based on reports of 1,039 people who have side effects when taking Azactam from the FDA, and is updated regularly.

What is Azactam?

Azactam has active ingredients of aztreonam. eHealthMe is studying from 1,044 Azactam users. Check the latest studies of Azactam.

What is Cholestasis?

Cholestasis (a condition where bile cannot flow from the liver to the duodenum) is found to be associated with 1,034 drugs and 1,808 conditions by eHealthMe. Check the latest studies of Cholestasis.

On Jul, 10, 2026

1,039 people reported to have side effects when taking Azactam.
Among them, 18 people (1.73%) have Cholestasis.

Among these 18 people:

How long have people been on Azactam when they have Cholestasis? *

What is the gender of people who have Cholestasis when taking Azactam? *

female: 55.56 %
male: 44.44 %

What is the age of people who have Cholestasis when taking Azactam? *

What are other drugs people take besides Azactam? *

What are other side effects people have besides Cholestasis? *

Hepatocellular Injury (liver injury): 7 people, 38.89%
Fever: 6 people, 33.33%
Thrombocytopenia (decrease of platelets in blood): 4 people, 22.22%
Bleeding Disorders: 3 people, 16.67%
Venoocclusive Liver Disease (small veins in the liver are obstructed): 3 people, 16.67%
Cytolytic Hepatitis (dissolution or destruction of a liver cell): 3 people, 16.67%
Multi-Organ Failure (multisystem organ failure): 3 people, 16.67%
Acute Kidney Failure: 3 people, 16.67%
Loss Of Consciousness: 3 people, 16.67%
Weight Increased: 2 people, 11.11%

What are the existing conditions these people have? *

Pyelonephritis Acute (sudden inflammation of kidney caused by bacteria): 3 people, 16.67%
Device Related Infection: 3 people, 16.67%
Psoas Abscess (collection of pus in the iliopsoas muscle compartment): 2 people, 11.11%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 2 people, 11.11%
Sedation: 1 person, 5.56%
Pseudomonal Bacteraemia (p. aeruginosa cause of bacterial infections of the blood): 1 person, 5.56%
Prostatitis (inflammation of the prostate gland): 1 person, 5.56%
Infection: 1 person, 5.56%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 1 person, 5.56%
Abscess Limb (limb infection): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Azactam and have Cholestasis?

- Check whether Cholestasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Azactam:

Azactam (1,044 reports)

Cholestasis treatments and more:

Cholestasis (23,731 reports)

Browse all side effects of Azactam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cholestasis:

Cholestasis (1,034 drugs)

Browse all the conditions that are associated with Cholestasis:

Cholestasis (1,808 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aztreonam (the active ingredients of Azactam) and Azactam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.