Azelastine and Cardiac failure - a phase IV clinical study of FDA data

Summary:

Cardiac failure is reported as a side effect among people who take Azelastine (azelastine hydrochloride), especially for people who are female, 60+ old, also take Aspirin, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Cardiac failure when taking Azelastine. It is created by eHealthMe based on reports of 17,147 people who have side effects when taking Azelastine from the FDA, and is updated regularly.

What is Azelastine?

Azelastine has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 17,400 Azelastine users. Check the latest studies of Azelastine.

What is Cardiac failure?

Cardiac failure is found to be associated with 2,055 drugs and 2,210 conditions by eHealthMe. Check the latest studies of Cardiac failure.

On Jul, 17, 2026

17,147 people reported to have side effects when taking Azelastine.
Among them, 31 people (0.18%) have Cardiac failure.

Among these 31 people:

What is the gender of people who have Cardiac failure when taking Azelastine? *

female: 70 %
male: 30 %

What is the age of people who have Cardiac failure when taking Azelastine? *

What are other drugs people take besides Azelastine? *

What are other side effects people have besides Cardiac failure? *

Dyspnea (difficult or laboured breathing): 7 people, 22.58%
Weight Decreased: 5 people, 16.13%
Acute Respiratory Failure: 5 people, 16.13%
Hypokalemia (low potassium): 5 people, 16.13%
Fatigue (feeling of tiredness): 4 people, 12.90%
Cough: 4 people, 12.90%
Anaemia (lack of blood): 4 people, 12.90%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 12.90%
Septic Shock (shock due to blood infection): 3 people, 9.68%
Pneumonia Pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa): 3 people, 9.68%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 12.90%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 3 people, 9.68%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 6.45%
Insomnia (sleeplessness): 2 people, 6.45%
Urination - Excessive Volume: 2 people, 6.45%
Asthma: 2 people, 6.45%
Type 2 Diabetes: 2 people, 6.45%
Seasonal Allergy (allergic condition due to certain season): 2 people, 6.45%
Stress And Anxiety: 2 people, 6.45%
Hypersensitivity: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Azelastine and have Cardiac failure?

- Check whether Cardiac failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Azelastine:

Azelastine (17,400 reports)

Cardiac failure treatments and more:

Cardiac failure (147,157 reports)

Browse all side effects of Azelastine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac failure:

Cardiac failure (2,055 drugs)

Browse all the conditions that are associated with Cardiac failure:

Cardiac failure (2,210 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on azelastine hydrochloride (the active ingredients of Azelastine) and Azelastine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.