Azelastine and Ear pain - a phase IV clinical study of FDA data

Summary:

Ear pain is reported as a side effect among people who take Azelastine (azelastine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Ear pain when taking Azelastine. It is created by eHealthMe based on reports of 17,147 people who have side effects when taking Azelastine from the FDA, and is updated regularly.

What is Azelastine?

Azelastine has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 17,400 Azelastine users. Check the latest studies of Azelastine.

What is Ear pain?

Ear pain is found to be associated with 1,392 drugs and 1,897 conditions by eHealthMe. Check the latest studies of Ear pain.

On Aug, 05, 2026

17,147 people reported to have side effects when taking Azelastine.
Among them, 63 people (0.37%) have Ear pain.

Among these 63 people:

How long have people been on Azelastine when they have Ear pain? *

What is the gender of people who have Ear pain when taking Azelastine? *

female: 96.72 %
male: 3.28 %

What is the age of people who have Ear pain when taking Azelastine? *

What are other drugs people take besides Azelastine? *

What are other side effects people have besides Ear pain? *

Nausea (feeling of having an urge to vomit): 33 people, 52.38%
Headache (pain in head): 21 people, 33.33%
Sinusitis (inflammation of sinus): 20 people, 31.75%
Fatigue (feeling of tiredness): 20 people, 31.75%
Fever: 19 people, 30.16%
Rashes (redness): 18 people, 28.57%
Oropharyngeal Pain: 17 people, 26.98%
Infusion Related Reaction: 16 people, 25.40%
Infection: 15 people, 23.81%
Pain: 15 people, 23.81%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 18 people, 28.57%
Asthma: 5 people, 7.94%
Immunodeficiency: 5 people, 7.94%
Birth Control: 5 people, 7.94%
High Blood Pressure: 4 people, 6.35%
Nasal Polyps (masses that develop in the lining of the nose): 4 people, 6.35%
Primary Immunodeficiency Syndrome: 4 people, 6.35%
Infection: 4 people, 6.35%
High Blood Cholesterol: 3 people, 4.76%
Immune System Disorder: 2 people, 3.17%

* Approximation only. Some reports may have incomplete information.

Do you take Azelastine and have Ear pain?

- Check whether Ear pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Azelastine:

Azelastine (17,400 reports)

Ear pain treatments and more:

Ear pain (26,025 reports)

Browse all side effects of Azelastine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ear pain:

Ear pain (1,392 drugs)

Browse all the conditions that are associated with Ear pain:

Ear pain (1,897 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on azelastine hydrochloride (the active ingredients of Azelastine) and Azelastine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.