Azithromycin and Adrenal insufficiency - a phase IV clinical study of FDA data

Summary:

Adrenal insufficiency is reported as a side effect among people who take Azithromycin (azithromycin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Asthma.

The phase IV clinical study analyzes which people have Adrenal insufficiency when taking Azithromycin. It is created by eHealthMe based on reports of 38,326 people who have side effects when taking Azithromycin from the FDA, and is updated regularly.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

What is Adrenal insufficiency?

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids) is found to be associated with 967 drugs and 1,092 conditions by eHealthMe. Check the latest studies of Adrenal insufficiency.

On Jul, 10, 2026

38,326 people reported to have side effects when taking Azithromycin.
Among them, 79 people (0.21%) have Adrenal insufficiency.

Could Azithromycin cause Adrenal insufficiency?

Among these 79 people:

How long have people been on Azithromycin when they have Adrenal insufficiency? *

What is the gender of people who have Adrenal insufficiency when taking Azithromycin? *

female: 43.24 %
male: 56.76 %

What is the age of people who have Adrenal insufficiency when taking Azithromycin? *

What are other drugs people take besides Azithromycin? *

What are other side effects people have besides Adrenal insufficiency? *

Dyspnea (difficult or laboured breathing): 25 people, 31.65%
Drug Ineffective: 23 people, 29.11%
Asthma: 22 people, 27.85%
Sleep Disorder: 19 people, 24.05%
Weight Loss: 19 people, 24.05%
Cough: 18 people, 22.78%
Pneumonia: 18 people, 22.78%
Pain In Extremity: 15 people, 18.99%
Vaginal Infection: 15 people, 18.99%
Rash Macular (small, flat red spots): 15 people, 18.99%

What are the existing conditions these people have? *

Asthma: 25 people, 31.65%
Hiv Infection: 12 people, 15.19%
Pneumocystis Jiroveci Pneumonia (fungal infection of the lungs): 7 people, 8.86%
Pulmonary Haemosiderosis (recurrent lungs bleeding): 5 people, 6.33%
Fungal Infection: 5 people, 6.33%
Vulvovaginal Candidiasis (vulvovaginal infection by fungi): 5 people, 6.33%
Nicotine Dependence: 4 people, 5.06%
Pneumonia: 4 people, 5.06%
Liver Disorder (liver diseases): 4 people, 5.06%
The Flu (the flu is caused by an influenza virus): 4 people, 5.06%

* Approximation only. Some reports may have incomplete information.

Do you take Azithromycin and have Adrenal insufficiency?

- Check whether Adrenal insufficiency is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Azithromycin:

Azithromycin (40,716 reports)

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adrenal insufficiency:

Adrenal insufficiency (967 drugs)

Browse all the conditions that are associated with Adrenal insufficiency:

Adrenal insufficiency (1,092 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on azithromycin (the active ingredients of Azithromycin) and Azithromycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.