Azithromycin and Nephrotic syndrome - a phase IV clinical study of FDA data

Summary:

Nephrotic syndrome is found among people who take Azithromycin, especially for people who are male, 20-29 old.

The phase IV clinical study analyzes which people take Azithromycin and have Nephrotic syndrome. It is created by eHealthMe based on reports of 24,512 people who have side effects when taking Azithromycin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Dec, 03, 2022

24,512 people reported to have side effects when taking Azithromycin.
Among them, 12 people (0.05%) have Nephrotic syndrome.


What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 26,833 Azithromycin users for its effectiveness, alternative drugs and more.

What is Nephrotic syndrome?

Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema) is found to be associated with 1,362 drugs and 973 conditions by eHealthMe.

Number of Azithromycin and Nephrotic syndrome reports submitted per year:

Could Azithromycin cause Nephrotic syndrome?

Gender of people who have Nephrotic syndrome when taking Azithromycin *:

  • female: 45.45 %
  • male: 54.55 %

Age of people who have Nephrotic syndrome when taking Azithromycin *:

  • 0-1: 0.0 %
  • 2-9: 27.27 %
  • 10-19: 9.09 %
  • 20-29: 36.36 %
  • 30-39: 18.18 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 9.09 %

Common drugs people take besides Azithromycin *:

  1. Tacrolimus: 6 people, 50.00%
  2. Lantus: 5 people, 41.67%
  3. Prednisolone: 4 people, 33.33%
  4. Simvastatin: 4 people, 33.33%
  5. Cotrim: 4 people, 33.33%
  6. Furosemide: 4 people, 33.33%
  7. Adalat: 4 people, 33.33%
  8. Apidra: 2 people, 16.67%
  9. Prednisone: 2 people, 16.67%
  10. Omeprazole: 2 people, 16.67%

Common side effects people have besides Nephrotic syndrome *:

  1. Renal Failure Chronic (long lasting kidney dysfunction): 2 people, 16.67%
  2. Proteinuria Present: 2 people, 16.67%
  3. Blood Albumin Decreased: 2 people, 16.67%
  4. Weight Increased: 1 person, 8.33%
  5. Emotional Distress: 1 person, 8.33%
  6. Glomerulonephritis Proliferative (a disorder of the glomeruli (glomerulonephritis), or small blood vessels in the kidneys): 1 person, 8.33%
  7. Glomerulonephritis Membranous (nephritis with inflammation of the capillary loops in the renal glomeruli): 1 person, 8.33%
  8. Glomerulonephritis Membranoproliferative (a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (gbm) thickening): 1 person, 8.33%
  9. Generalised Oedema (swelling all over the body): 1 person, 8.33%
  10. General Physical Health Deterioration (weak health status): 1 person, 8.33%

Common conditions people have *:

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 25.00%
  2. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 2 people, 16.67%
  3. Pancreatic Insufficiency: 2 people, 16.67%
  4. Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 2 people, 16.67%
  5. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 2 people, 16.67%
  6. Diabetes: 2 people, 16.67%
  7. Cystic Fibrosis (disease of the secretary glands): 2 people, 16.67%
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 16.67%
  9. Sinus Headache (headache caused by sinus infections): 1 person, 8.33%
  10. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Azithromycin and have Nephrotic syndrome?

Check whether Nephrotic syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Nephrotic syndrome and when was it recovered:

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Alternative drugs to, pros and cons of Azithromycin:

Common Azithromycin side effects:

Browse all side effects of Azithromycin:

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Nephrotic syndrome treatments and more:

COVID vaccines that are related to Nephrotic syndrome:

Common drugs associated with Nephrotic syndrome:

All the drugs that are associated with Nephrotic syndrome:

Common conditions associated with Nephrotic syndrome:

All the conditions that are associated with Nephrotic syndrome:

How the study uses the data?

The study uses data from the FDA. It is based on azithromycin (the active ingredients of Azithromycin) and Azithromycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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