Azithromycin and Serum sickness - a phase IV clinical study of FDA data

Summary:

Serum sickness is reported as a side effect among people who take Azithromycin (azithromycin), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Tobramycin, and have Staphylococcal infection.

The phase IV clinical study analyzes which people have Serum sickness when taking Azithromycin. It is created by eHealthMe based on reports of 38,326 people who have side effects when taking Azithromycin from the FDA, and is updated regularly.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

What is Serum sickness?

Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum) is found to be associated with 270 drugs and 489 conditions by eHealthMe. Check the latest studies of Serum sickness.

On Aug, 11, 2026

38,326 people reported to have side effects when taking Azithromycin.
Among them, 14 people (0.04%) have Serum sickness.

Could Azithromycin cause Serum sickness?

Among these 14 people:

How long have people been on Azithromycin when they have Serum sickness? *

What is the gender of people who have Serum sickness when taking Azithromycin? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Serum sickness when taking Azithromycin? *

What are other drugs people take besides Azithromycin? *

What are other side effects people have besides Serum sickness? *

Fever: 9 people, 64.29%
Malaise (a feeling of general discomfort or uneasiness): 9 people, 64.29%
Renal Impairment (severely reduced kidney function): 6 people, 42.86%
Feeling Abnormal: 6 people, 42.86%
Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 6 people, 42.86%
Aphagia (inability or refusal to swallow): 6 people, 42.86%
Laryngeal Oedema (swelling of larynx): 3 people, 21.43%
Hepatomegaly (abnormal enlargement of the liver): 3 people, 21.43%
Hyperkalemia (damage to or disease of the kidney): 3 people, 21.43%
Abnormal Behavior: 3 people, 21.43%

What are the existing conditions these people have? *

Staphylococcal Infection (an infection with staphylococcus bacteria): 5 people, 35.71%
Immunodeficiency Common Variable: 2 people, 14.29%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 14.29%
Transplant Rejection (a transplant material is not worked): 1 person, 7.14%
Pain: 1 person, 7.14%
Otitis (ear infection): 1 person, 7.14%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Azithromycin and have Serum sickness?

- Check whether Serum sickness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Azithromycin:

Azithromycin (40,716 reports)

Serum sickness treatments and more:

Serum sickness (3,679 reports)

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Serum sickness:

Serum sickness (270 drugs)

Browse all the conditions that are associated with Serum sickness:

Serum sickness (489 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on azithromycin (the active ingredients of Azithromycin) and Azithromycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.