Azopt and Epidermal necrosis - a phase IV clinical study of FDA data

Summary:

Epidermal necrosis is reported as a side effect among people who take Azopt (brinzolamide), especially for people who are female, 60+ old, also take Pregabalin, and have Dyslipidaemia.

The phase IV clinical study analyzes which people have Epidermal necrosis when taking Azopt. It is created by eHealthMe based on reports of 7,917 people who have side effects when taking Azopt from the FDA, and is updated regularly.

What is Azopt?

Azopt has active ingredients of brinzolamide. It is often used in glaucoma. eHealthMe is studying from 8,058 Azopt users. Check the latest studies of Azopt.

What is Epidermal necrosis?

Epidermal necrosis (skin condition that is usually caused by a reaction to drugs) is found to be associated with 140 drugs and 320 conditions by eHealthMe. Check the latest studies of Epidermal necrosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

7,917 people reported to have side effects when taking Azopt.
Among them, 11 people (0.14%) have Epidermal necrosis.

Among these 11 people:

What is the gender of people who have Epidermal necrosis when taking Azopt? *

female: 100 %
male: 0.0 %

What is the age of people who have Epidermal necrosis when taking Azopt? *

What are other drugs people take besides Azopt? *

What are other side effects people have besides Epidermal necrosis? *

Rash Papular (redness with papule): 11 people, 100.00%
Haemoglobin Decreased: 11 people, 100.00%
Erythema Multiforme (a type of hypersensitivity reaction): 11 people, 100.00%
Rash Erythematous (redness of the skin): 9 people, 81.82%
Nikolsky's Sign: 6 people, 54.55%

What are the existing conditions these people have? *

Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 11 people, 100.00%
Menopausal Symptoms: 11 people, 100.00%
Joint Pain: 11 people, 100.00%
High Blood Pressure: 11 people, 100.00%
Dyslipidaemia (abnormal amount of lipids): 11 people, 100.00%
Insomnia (sleeplessness): 10 people, 90.91%
Sinusitis (inflammation of sinus): 9 people, 81.82%

* Approximation only. Some reports may have incomplete information.

Do you take Azopt and have Epidermal necrosis?

- Check whether Epidermal necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Azopt:

Azopt (8,058 reports)

Browse all side effects of Azopt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Epidermal necrosis:

Epidermal necrosis (140 drugs)

Browse all the conditions that are associated with Epidermal necrosis:

Epidermal necrosis (320 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on brinzolamide (the active ingredients of Azopt) and Azopt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.