Azulfidine and Septic shock - a phase IV clinical study of FDA data

Summary:

Septic shock is reported as a side effect among people who take Azulfidine (sulfasalazine), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Prednisolone, and have High blood pressure.

The phase IV clinical study analyzes which people have Septic shock when taking Azulfidine. It is created by eHealthMe based on reports of 7,893 people who have side effects when taking Azulfidine from the FDA, and is updated regularly.

What is Azulfidine?

Azulfidine has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis. eHealthMe is studying from 7,997 Azulfidine users. Check the latest studies of Azulfidine.

What is Septic shock?

Septic shock (shock due to blood infection) is found to be associated with 1,734 drugs and 3,398 conditions by eHealthMe. Check the latest studies of Septic shock.



On Aug, 05, 2026

7,893 people reported to have side effects when taking Azulfidine.
Among them, 42 people (0.53%) have Septic shock.

Could Azulfidine cause Septic shock?

Among these 42 people:

How long have people been on Azulfidine when they have Septic shock? *

  • < 1 month: 26.32 %
  • 1 - 6 months: 47.37 %
  • 6 - 12 months: 10.53 %
  • 1 - 2 years: 5.26 %
  • 2 - 5 years: 10.53 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Septic shock when taking Azulfidine? *

  • female: 56.1 %
  • male: 43.9 %

What is the age of people who have Septic shock when taking Azulfidine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 7.69 %
  • 60+: 92.31 %

What are other drugs people take besides Azulfidine? *

  1. Prednisolone: 12 people, 28.57%
  2. Lansoprazole: 7 people, 16.67%
  3. Actemra: 5 people, 11.90%
  4. Xeljanz: 5 people, 11.90%
  5. Olmesartan Medoxomil: 5 people, 11.90%
  6. Orencia: 5 people, 11.90%
  7. Alendronate Sodium: 4 people, 9.52%
  8. Aspirin: 4 people, 9.52%
  9. Famotidine: 4 people, 9.52%
  10. Tacrolimus: 4 people, 9.52%

What are other side effects people have besides Septic shock? *

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 9 people, 21.43%
  2. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 8 people, 19.05%
  3. Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 8 people, 19.05%
  4. Pneumonia: 7 people, 16.67%
  5. Fever: 6 people, 14.29%
  6. Urinary Tract Infection: 5 people, 11.90%
  7. Pneumonia Bacterial (pneumonia associated with bacterial infection): 5 people, 11.90%
  8. Anaemia (lack of blood): 5 people, 11.90%
  9. Hypokalemia (low potassium): 5 people, 11.90%
  10. Leukopenia (less number of white blood cells in blood): 5 people, 11.90%

What are the existing conditions these people have? *

  1. High Blood Pressure: 16 people, 38.10%
  2. Osteoporosis (bones weak and more likely to break): 12 people, 28.57%
  3. Cerebral Infarction (less blood supply to brain resulting tissue damage): 6 people, 14.29%
  4. Gastric Ulcer (stomach ulcer): 6 people, 14.29%
  5. Asthma: 5 people, 11.90%
  6. Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 11.90%
  7. Oral Candidiasis (fungal infection of mouth): 3 people, 7.14%
  8. Insomnia (sleeplessness): 3 people, 7.14%
  9. Stress And Anxiety: 3 people, 7.14%
  10. Oral Herpes (viral infection of mouth): 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Azulfidine and have Septic shock?

- Check whether Septic shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Azulfidine:

Septic shock treatments and more:

How severe was Septic shock and when was it recovered:

Expand to all the drugs that have ingredients of sulfasalazine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Azulfidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Septic shock:

Browse all the conditions that are associated with Septic shock:


How the study uses the data?

The study uses data from the FDA. It is based on sulfasalazine (the active ingredients of Azulfidine) and Azulfidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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