B12 and Endometriosis - a phase IV clinical study of FDA data

Summary:

Endometriosis is reported as a side effect among people who take B12 (cobalamin), especially for people who are 40-49 old, have been taking the drug for 2 - 5 years also take Amlodipine, and have Acromegaly.

The phase IV clinical study analyzes which people have Endometriosis when taking B12. It is created by eHealthMe based on reports of 119,647 people who have side effects when taking B12 from the FDA, and is updated regularly.

What is B12?

B12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,894 B12 users. Check the latest studies of B12.

What is Endometriosis?

Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain) is found to be associated with 423 drugs and 561 conditions by eHealthMe. Check the latest studies of Endometriosis.

On Jul, 19, 2026

119,647 people reported to have side effects when taking B12.
Among them, 73 people (0.06%) have Endometriosis.

Among these 73 people:

How long have people been on B12 when they have Endometriosis? *

What is the age of people who have Endometriosis when taking B12? *

What are other drugs people take besides B12? *

What are other side effects people have besides Endometriosis? *

Headache (pain in head): 27 people, 36.99%
Dizziness: 26 people, 35.62%
Abdominal Pain: 25 people, 34.25%
Weight Increased: 24 people, 32.88%
Depression: 24 people, 32.88%
Peripheral Swelling: 22 people, 30.14%
Weakness: 22 people, 30.14%
Feeling Abnormal: 21 people, 28.77%
Renal Disorder (kidney disease): 21 people, 28.77%
Back Injury: 21 people, 28.77%

What are the existing conditions these people have? *

Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 17 people, 23.29%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 15 people, 20.55%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 17.81%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 10.96%
Pain: 8 people, 10.96%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 8.22%
Nausea (feeling of having an urge to vomit): 5 people, 6.85%
Immune System Disorder: 4 people, 5.48%
Migraine (headache): 4 people, 5.48%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

Do you take B12 and have Endometriosis?

- Check whether Endometriosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to B12:

B12 (121,894 reports)

Endometriosis treatments and more:

Endometriosis (19,678 reports)

Browse all side effects of B12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Endometriosis:

Endometriosis (423 drugs)

Browse all the conditions that are associated with Endometriosis:

Endometriosis (561 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cobalamin (the active ingredients of B12) and B12 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.