B6 and Hypoaesthesia - a phase IV clinical study of FDA data

Summary:

Hypoaesthesia is reported as a side effect among people who take B6 (pyridoxine (vitamin b6)), especially for people who are female, 60+ old, also take Vitamin B12, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Hypoaesthesia when taking B6. It is created by eHealthMe based on reports of 931 people who have side effects when taking B6 from the FDA, and is updated regularly.

What is B6?

B6 has active ingredients of pyridoxine (vitamin b6). eHealthMe is studying from 1,043 B6 users. Check the latest studies of B6.

What is Hypoaesthesia?

Hypoaesthesia (reduced sense of touch or sensation) is found to be associated with 2,899 drugs and 3,184 conditions by eHealthMe. Check the latest studies of Hypoaesthesia.

On Jul, 13, 2026

931 people reported to have side effects when taking B6.
Among them, 27 people (2.9%) have Hypoaesthesia.

Among these 27 people:

What is the gender of people who have Hypoaesthesia when taking B6? *

female: 70.37 %
male: 29.63 %

What is the age of people who have Hypoaesthesia when taking B6? *

What are other drugs people take besides B6? *

What are other side effects people have besides Hypoaesthesia? *

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 14 people, 51.85%
Pain In Extremity: 9 people, 33.33%
Pain: 7 people, 25.93%
Fatigue (feeling of tiredness): 6 people, 22.22%
Gait Disturbance: 6 people, 22.22%
Back Pain: 5 people, 18.52%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 5 people, 18.52%
Muscle Tightness: 5 people, 18.52%
Affective Disorder (mental disorder): 4 people, 14.81%
Dyspnea (difficult or laboured breathing): 4 people, 14.81%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 25.93%
Asthma: 6 people, 22.22%
Stress And Anxiety: 6 people, 22.22%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 22.22%
High Blood Pressure: 5 people, 18.52%
Joint Pain: 5 people, 18.52%
Weakness: 4 people, 14.81%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 14.81%
Hypersensitivity: 4 people, 14.81%
Inflammation: 4 people, 14.81%

* Approximation only. Some reports may have incomplete information.

Do you take B6 and have Hypoaesthesia?

- Check whether Hypoaesthesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to B6:

B6 (1,043 reports)

Hypoaesthesia treatments and more:

Hypoaesthesia (189,312 reports)

Browse all side effects of B6:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoaesthesia:

Hypoaesthesia (2,899 drugs)

Browse all the conditions that are associated with Hypoaesthesia:

Hypoaesthesia (3,184 conditions)

Related publications that referenced our studies

Hassan JK, "POTENTIAL POSITIVE EFFECT OF ORAL PYRIDOXINE ALONE AND IN COMBINATION WITH MECLIZINE ON CIGARETTES SMOKING DURING TENDAYS’TRIAL", IJPSR, 2015 Jan .
Hassan JK, "POTENTIAL POSITIVE EFFECT OF ORAL PYRIDOXINE ALONE AND IN COMBINATION WITH MECLIZINE ON CIGARETTES SMOKING DURING TENDAYS’TRIAL", IJPSR, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on pyridoxine (vitamin b6) (the active ingredients of B6) and B6 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.