Baclofen and Angle closure glaucoma - a phase IV clinical study of FDA data

Summary:

Angle closure glaucoma is reported as a side effect among people who take Baclofen (baclofen), especially for people who are female, 50-59 old, also take Topamax, and have Narcolepsy.

The phase IV clinical study analyzes which people have Angle closure glaucoma when taking Baclofen. It is created by eHealthMe based on reports of 106,082 people who have side effects when taking Baclofen from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,661 Baclofen users. Check the latest studies of Baclofen.

What is Angle closure glaucoma?

Angle closure glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity) is found to be associated with 217 drugs and 479 conditions by eHealthMe. Check the latest studies of Angle closure glaucoma.

On May, 04, 2026

106,082 people reported to have side effects when taking Baclofen.
Among them, 18 people (0.02%) have Angle closure glaucoma.

Could Baclofen cause Angle closure glaucoma?

Among these 18 people:

What is the gender of people who have Angle closure glaucoma when taking Baclofen? *

female: 100 %
male: 0.0 %

What is the age of people who have Angle closure glaucoma when taking Baclofen? *

What are other drugs people take besides Baclofen? *

What are other side effects people have besides Angle closure glaucoma? *

Cataract (clouding of the lens inside the eye): 4 people, 22.22%
Headache (pain in head): 3 people, 16.67%
Tinnitus (a ringing in the ears): 3 people, 16.67%
Fatigue (feeling of tiredness): 3 people, 16.67%
Visual Impairment: 3 people, 16.67%
High Blood Pressure: 2 people, 11.11%
High Blood Cholesterol: 2 people, 11.11%
Hepatitis (inflammation of the liver): 2 people, 11.11%
Hepatic Enzyme Increased: 2 people, 11.11%
Fall: 2 people, 11.11%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 16.67%
Breast Cancer: 2 people, 11.11%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 11.11%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 11.11%
Menopause (end of monthly cycles in women): 2 people, 11.11%
Insomnia (sleeplessness): 2 people, 11.11%
High Blood Cholesterol: 2 people, 11.11%
Headache (pain in head): 1 person, 5.56%
Depression: 1 person, 5.56%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Baclofen and have Angle closure glaucoma?

- Check whether Angle closure glaucoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Baclofen:

Baclofen (108,661 reports)

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angle closure glaucoma:

Angle closure glaucoma (217 drugs)

Browse all the conditions that are associated with Angle closure glaucoma:

Angle closure glaucoma (479 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on baclofen (the active ingredients of Baclofen) and Baclofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.