Baclofen and Sick sinus syndrome - a phase IV clinical study of FDA data

Summary:

Sick sinus syndrome is reported as a side effect among people who take Baclofen (baclofen), especially for people who are male, 60+ old, also take Carbamazepine, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Sick sinus syndrome when taking Baclofen. It is created by eHealthMe based on reports of 106,082 people who have side effects when taking Baclofen from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Sick sinus syndrome?

Sick sinus syndrome (a collection of heart rhythm disorders) is found to be associated with 580 drugs and 842 conditions by eHealthMe. Check the latest studies of Sick sinus syndrome.

On Jul, 07, 2026

106,082 people reported to have side effects when taking Baclofen.
Among them, 27 people (0.03%) have Sick sinus syndrome.

Could Baclofen cause Sick sinus syndrome?

Among these 27 people:

What is the gender of people who have Sick sinus syndrome when taking Baclofen? *

female: 36 %
male: 64 %

What is the age of people who have Sick sinus syndrome when taking Baclofen? *

What are other drugs people take besides Baclofen? *

What are other side effects people have besides Sick sinus syndrome? *

Fall: 13 people, 48.15%
Hypotension (abnormally low blood pressure): 12 people, 44.44%
Conduction Disorder (serious disorder of the heart not responses proper to impulses): 11 people, 40.74%
Overdose: 11 people, 40.74%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 10 people, 37.04%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 25.93%
Diarrhea: 5 people, 18.52%
Fainting (loss of consciousness and postural tone): 5 people, 18.52%
Bradycardia (abnormally slow heart action): 5 people, 18.52%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 4 people, 14.81%

What are the existing conditions these people have? *

Heart Palpitations (feelings or sensations that your heart is pounding or racing): 3 people, 11.11%
Bipolar Disorder (mood disorder): 3 people, 11.11%
Multiple Myeloma (cancer of the plasma cells): 2 people, 7.41%
Constipation: 2 people, 7.41%
Enlarged Prostate: 2 people, 7.41%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 7.41%
Haemorrhoidal Haemorrhage (bleeding from the haemorrhoids): 2 people, 7.41%
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 2 people, 7.41%
Agitation (state of anxiety or nervous excitement): 2 people, 7.41%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Baclofen and have Sick sinus syndrome?

- Check whether Sick sinus syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Baclofen:

Baclofen (108,662 reports)

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sick sinus syndrome:

Sick sinus syndrome (580 drugs)

Browse all the conditions that are associated with Sick sinus syndrome:

Sick sinus syndrome (842 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on baclofen (the active ingredients of Baclofen) and Baclofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.