Bactrim ds and Macrocytosis - a phase IV clinical study of FDA data

Summary:

Macrocytosis is reported as a side effect among people who take Bactrim ds (sulfamethoxazole; trimethoprim), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Zoloft, and have Depression.

The phase IV clinical study analyzes which people have Macrocytosis when taking Bactrim ds. It is created by eHealthMe based on reports of 16,059 people who have side effects when taking Bactrim ds from the FDA, and is updated regularly.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.

What is Macrocytosis?

Macrocytosis (enlargement of red blood cells with near-constant haemoglobin concentration) is found to be associated with 306 drugs and 585 conditions by eHealthMe. Check the latest studies of Macrocytosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

16,059 people reported to have side effects when taking Bactrim ds.
Among them, 12 people (0.07%) have Macrocytosis.

Among these 12 people:

How long have people been on Bactrim ds when they have Macrocytosis? *

What is the gender of people who have Macrocytosis when taking Bactrim ds? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Macrocytosis when taking Bactrim ds? *

What are other drugs people take besides Bactrim ds? *

What are other side effects people have besides Macrocytosis? *

Rashes (redness): 8 people, 66.67%
Nausea (feeling of having an urge to vomit): 8 people, 66.67%
Fatigue (feeling of tiredness): 8 people, 66.67%
Nausea And Vomiting: 8 people, 66.67%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 7 people, 58.33%
Muscle Spasms (muscle contraction): 7 people, 58.33%
Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 7 people, 58.33%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 6 people, 50.00%
Insomnia (sleeplessness): 6 people, 50.00%
Blood Bilirubin Increased: 6 people, 50.00%

What are the existing conditions these people have? *

Sleep Disorder: 6 people, 50.00%
Menopause (end of monthly cycles in women): 6 people, 50.00%
Depression: 6 people, 50.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 16.67%
Transplant Rejection (a transplant material is not worked): 1 person, 8.33%
Ovarian Cancer (cancer of ovary): 1 person, 8.33%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 8.33%
Malignant Neoplasm Of Uterine Adnexa (cancer tumour of uterus surrounding ,ovaries ,fallopian tubes ,ligaments): 1 person, 8.33%
Insomnia (sleeplessness): 1 person, 8.33%
Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim ds and have Macrocytosis?

- Check whether Macrocytosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim ds:

Bactrim ds (17,027 reports)

Macrocytosis treatments and more:

Macrocytosis (2,166 reports)

How severe was Macrocytosis and when was it recovered:

Macrocytosis in Bactrim ds

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Macrocytosis and drugs with ingredients of sulfamethoxazole; trimethoprim (111 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim ds:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Macrocytosis:

Macrocytosis (306 drugs)

Browse all the conditions that are associated with Macrocytosis:

Macrocytosis (585 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim ds) and Bactrim ds (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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